Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QDW67_RS10050 Genome accession   NZ_CP122681
Coordinates   2076945..2077601 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ETEC4068     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2071945..2082601
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QDW67_RS10020 (QDW67_10020) dcyD 2072826..2073812 (+) 987 WP_063086320.1 D-cysteine desulfhydrase -
  QDW67_RS10025 (QDW67_10025) tcyL 2073827..2074495 (+) 669 WP_063086323.1 cystine ABC transporter permease -
  QDW67_RS10030 (QDW67_10030) tcyN 2074492..2075244 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QDW67_RS10035 (QDW67_10035) sdiA 2075473..2076195 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  QDW67_RS10040 (QDW67_10040) yecF 2076262..2076486 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QDW67_RS10045 (QDW67_10045) yecU 2076473..2076649 (-) 177 WP_000590347.1 protein YecU -
  QDW67_RS10050 (QDW67_10050) letA 2076945..2077601 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QDW67_RS10055 (QDW67_10055) uvrC 2077598..2079430 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QDW67_RS10060 (QDW67_10060) pgsA 2079487..2080035 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QDW67_RS10080 (QDW67_10080) yecA 2080685..2081350 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=742349 QDW67_RS10050 WP_000611328.1 2076945..2077601(+) (letA) [Escherichia coli strain ETEC4068]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=742349 QDW67_RS10050 WP_000611328.1 2076945..2077601(+) (letA) [Escherichia coli strain ETEC4068]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482