Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QDW53_RS10385 Genome accession   NZ_CP122679
Coordinates   2124571..2125227 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain ETEC4069     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2119571..2130227
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QDW53_RS10355 (QDW53_10355) dcyD 2120452..2121438 (+) 987 WP_063086320.1 D-cysteine desulfhydrase -
  QDW53_RS10360 (QDW53_10360) tcyL 2121453..2122121 (+) 669 WP_192297623.1 cystine ABC transporter permease -
  QDW53_RS10365 (QDW53_10365) tcyN 2122118..2122870 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QDW53_RS10370 (QDW53_10370) sdiA 2123099..2123821 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  QDW53_RS10375 (QDW53_10375) yecF 2123888..2124112 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QDW53_RS10380 (QDW53_10380) yecU 2124099..2124275 (-) 177 WP_000590347.1 protein YecU -
  QDW53_RS10385 (QDW53_10385) letA 2124571..2125227 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QDW53_RS10390 (QDW53_10390) uvrC 2125224..2127056 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QDW53_RS10395 (QDW53_10395) pgsA 2127113..2127661 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QDW53_RS10415 (QDW53_10415) yecA 2128311..2128976 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=742268 QDW53_RS10385 WP_000611328.1 2124571..2125227(+) (letA) [Escherichia coli strain ETEC4069]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=742268 QDW53_RS10385 WP_000611328.1 2124571..2125227(+) (letA) [Escherichia coli strain ETEC4069]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482