Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QDW64_RS09580 Genome accession   NZ_CP122625
Coordinates   1943995..1944651 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ETEC4089     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1938995..1949651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QDW64_RS09550 (QDW64_09550) dcyD 1939875..1940861 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QDW64_RS09555 (QDW64_09555) tcyL 1940876..1941544 (+) 669 WP_001158218.1 cystine ABC transporter permease -
  QDW64_RS09560 (QDW64_09560) tcyN 1941541..1942293 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QDW64_RS09565 (QDW64_09565) sdiA 1942523..1943245 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  QDW64_RS09570 (QDW64_09570) yecF 1943312..1943536 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QDW64_RS09575 (QDW64_09575) yecU 1943523..1943699 (-) 177 WP_001326718.1 protein YecU -
  QDW64_RS23785 - 1943782..1943853 (-) 72 Protein_1871 transcriptional regulator -
  QDW64_RS09580 (QDW64_09580) letA 1943995..1944651 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QDW64_RS09585 (QDW64_09585) uvrC 1944648..1946480 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QDW64_RS09590 (QDW64_09590) pgsA 1946537..1947085 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QDW64_RS09610 (QDW64_09610) - 1947850..1948547 (+) 698 WP_151884388.1 IS1 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=741535 QDW64_RS09580 WP_000611335.1 1943995..1944651(+) (letA) [Escherichia coli strain ETEC4089]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=741535 QDW64_RS09580 WP_000611335.1 1943995..1944651(+) (letA) [Escherichia coli strain ETEC4089]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCAGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACTAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486