Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QDW52_RS09370 Genome accession   NZ_CP122617
Coordinates   1945767..1946423 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain ETEC4091     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1940767..1951423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QDW52_RS09340 (QDW52_09340) dcyD 1941646..1942632 (+) 987 WP_001128213.1 D-cysteine desulfhydrase -
  QDW52_RS09345 (QDW52_09345) tcyL 1942647..1943315 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QDW52_RS09350 (QDW52_09350) tcyN 1943312..1944064 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QDW52_RS09355 (QDW52_09355) sdiA 1944294..1945016 (+) 723 WP_001154287.1 transcriptional regulator SdiA -
  QDW52_RS09360 (QDW52_09360) yecF 1945084..1945308 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QDW52_RS09365 (QDW52_09365) yecU 1945295..1945471 (-) 177 WP_000590347.1 protein YecU -
  QDW52_RS24625 - 1945509..1945625 (-) 117 WP_001302039.1 hypothetical protein -
  QDW52_RS09370 (QDW52_09370) letA 1945767..1946423 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QDW52_RS09375 (QDW52_09375) uvrC 1946420..1948252 (+) 1833 WP_282842869.1 excinuclease ABC subunit UvrC Machinery gene
  QDW52_RS09380 (QDW52_09380) pgsA 1948309..1948857 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QDW52_RS09400 (QDW52_09400) yecA 1949507..1950172 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=741371 QDW52_RS09370 WP_000611335.1 1945767..1946423(+) (letA) [Escherichia coli strain ETEC4091]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=741371 QDW52_RS09370 WP_000611335.1 1945767..1946423(+) (letA) [Escherichia coli strain ETEC4091]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
TAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCTAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486