Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QCL60_RS09295 Genome accession   NZ_CP122517
Coordinates   1942333..1942989 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain MY1-8     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1937333..1947989
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QCL60_RS09265 (QCL60_09265) dcyD 1938212..1939198 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QCL60_RS09270 (QCL60_09270) tcyL 1939213..1939881 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QCL60_RS09275 (QCL60_09275) tcyN 1939878..1940630 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QCL60_RS09280 (QCL60_09280) sdiA 1940860..1941582 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  QCL60_RS09285 (QCL60_09285) yecF 1941650..1941874 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QCL60_RS09290 (QCL60_09290) yecU 1941861..1942037 (-) 177 WP_000590344.1 protein YecU -
  QCL60_RS24530 - 1942075..1942191 (-) 117 WP_001302039.1 hypothetical protein -
  QCL60_RS09295 (QCL60_09295) letA 1942333..1942989 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QCL60_RS09300 (QCL60_09300) uvrC 1942986..1944818 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  QCL60_RS09305 (QCL60_09305) pgsA 1944875..1945423 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QCL60_RS09325 (QCL60_09325) yecA 1946072..1946737 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=741048 QCL60_RS09295 WP_000611328.1 1942333..1942989(+) (letA) [Escherichia coli strain MY1-8]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=741048 QCL60_RS09295 WP_000611328.1 1942333..1942989(+) (letA) [Escherichia coli strain MY1-8]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482