Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QC808_RS09685 Genome accession   NZ_CP122503
Coordinates   2019941..2020597 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain W619     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2014941..2025597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QC808_RS09655 dcyD 2015821..2016807 (+) 987 WP_001128242.1 D-cysteine desulfhydrase -
  QC808_RS09660 tcyL 2016822..2017490 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QC808_RS09665 tcyN 2017487..2018239 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QC808_RS09670 sdiA 2018469..2019191 (+) 723 WP_040234759.1 transcriptional regulator SdiA -
  QC808_RS09675 yecF 2019258..2019482 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QC808_RS09680 yecU 2019469..2019645 (-) 177 WP_000590344.1 protein YecU -
  QC808_RS24960 - 2019683..2019799 (-) 117 WP_001302039.1 hypothetical protein -
  QC808_RS09685 letA 2019941..2020597 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QC808_RS09690 uvrC 2020594..2022426 (+) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  QC808_RS09695 pgsA 2022483..2023031 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QC808_RS09715 yecA 2023681..2024346 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=740809 QC808_RS09685 WP_000611328.1 2019941..2020597(+) (letA) [Escherichia coli strain W619]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=740809 QC808_RS09685 WP_000611328.1 2019941..2020597(+) (letA) [Escherichia coli strain W619]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482