Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QC809_RS09850 Genome accession   NZ_CP122499
Coordinates   1994350..1995006 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain W409     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1989350..2000006
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QC809_RS09820 dcyD 1990229..1991215 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QC809_RS09825 tcyL 1991230..1991898 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QC809_RS09830 tcyN 1991895..1992647 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QC809_RS09835 sdiA 1992877..1993599 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  QC809_RS09840 yecF 1993667..1993891 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QC809_RS09845 yecU 1993878..1994054 (-) 177 WP_000590344.1 protein YecU -
  QC809_RS24970 - 1994092..1994208 (-) 117 Protein_1921 transcriptional regulator -
  QC809_RS09850 letA 1994350..1995006 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QC809_RS09855 uvrC 1995003..1996835 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QC809_RS09860 pgsA 1996892..1997440 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QC809_RS09880 yecA 1998089..1998754 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=740729 QC809_RS09850 WP_000611328.1 1994350..1995006(+) (letA) [Escherichia coli strain W409]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=740729 QC809_RS09850 WP_000611328.1 1994350..1995006(+) (letA) [Escherichia coli strain W409]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482