Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   QC805_RS08930 Genome accession   NZ_CP122496
Coordinates   1841324..1841980 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain a7     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1836324..1846980
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QC805_RS08900 dcyD 1837203..1838189 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  QC805_RS08905 tcyL 1838204..1838872 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  QC805_RS08910 tcyN 1838869..1839621 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  QC805_RS08915 sdiA 1839851..1840573 (+) 723 WP_001154260.1 transcriptional regulator SdiA -
  QC805_RS08920 yecF 1840641..1840865 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  QC805_RS08925 yecU 1840852..1841028 (-) 177 WP_000590344.1 protein YecU -
  QC805_RS23420 - 1841066..1841182 (-) 117 WP_001302039.1 hypothetical protein -
  QC805_RS08930 letA 1841324..1841980 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  QC805_RS08935 uvrC 1841977..1843809 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  QC805_RS08940 pgsA 1843866..1844414 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  QC805_RS08960 yecA 1845064..1845729 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=740651 QC805_RS08930 WP_000611328.1 1841324..1841980(+) (letA) [Escherichia coli strain a7]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=740651 QC805_RS08930 WP_000611328.1 1841324..1841980(+) (letA) [Escherichia coli strain a7]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482