Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QBE57_RS06735 Genome accession   NZ_CP121670
Coordinates   1368514..1369155 (-) Length   213 a.a.
NCBI ID   WP_171935712.1    Uniprot ID   -
Organism   Streptococcus suis strain HBXY-SL     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1363514..1374155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QBE57_RS06710 comFA/cflA 1363668..1364960 (-) 1293 WP_012774986.1 DEAD/DEAH box helicase Machinery gene
  QBE57_RS06715 - 1365017..1365649 (+) 633 WP_014636235.1 YigZ family protein -
  QBE57_RS06720 cysK 1365739..1366665 (+) 927 WP_012774985.1 cysteine synthase A -
  QBE57_RS06725 - 1366691..1367062 (-) 372 WP_011921997.1 S1 RNA-binding domain-containing protein -
  QBE57_RS06730 - 1367064..1368464 (-) 1401 WP_011921996.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  QBE57_RS06735 vraR 1368514..1369155 (-) 642 WP_171935712.1 response regulator transcription factor Regulator
  QBE57_RS06740 - 1369127..1370143 (-) 1017 WP_002937028.1 sensor histidine kinase -
  QBE57_RS06745 liaF 1370140..1370799 (-) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  QBE57_RS06750 - 1371256..1371744 (-) 489 WP_395333372.1 PASTA domain-containing protein -
  QBE57_RS06755 pknB 1371721..1373250 (-) 1530 Protein_1330 Stk1 family PASTA domain-containing Ser/Thr kinase -
  QBE57_RS06760 - 1373250..1373987 (-) 738 WP_012774983.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23789.38 Da        Isoelectric Point: 5.0119

>NTDB_id=738581 QBE57_RS06735 WP_171935712.1 1368514..1369155(-) (vraR) [Streptococcus suis strain HBXY-SL]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLNNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=738581 QBE57_RS06735 WP_171935712.1 1368514..1369155(-) (vraR) [Streptococcus suis strain HBXY-SL]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGCCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCGTTAGAGGTTAAACCTGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACTCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAAATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATATCCTTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.408