Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ODS73_RS02305 Genome accession   NZ_CP107038
Coordinates   421970..422659 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain BM6001     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 416970..427659
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ODS73_RS02280 (ODS73_02280) gpsB 417079..417408 (+) 330 WP_000146522.1 cell division regulator GpsB -
  ODS73_RS02290 (ODS73_02290) - 417894..419051 (+) 1158 WP_000711385.1 class I SAM-dependent RNA methyltransferase -
  ODS73_RS02295 (ODS73_02295) mapZ 419064..420458 (+) 1395 WP_000039254.1 mid-cell-anchored protein MapZ -
  ODS73_RS02300 (ODS73_02300) gndA 420534..421958 (+) 1425 WP_000158792.1 NADP-dependent phosphogluconate dehydrogenase -
  ODS73_RS02305 (ODS73_02305) covR 421970..422659 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  ODS73_RS02310 (ODS73_02310) cbpC 422757..423719 (+) 963 WP_000698035.1 choline-binding protein CbpC -
  ODS73_RS02315 (ODS73_02315) cbpJ 423738..424736 (+) 999 WP_000771128.1 choline-binding protein CbpJ -
  ODS73_RS02320 (ODS73_02320) - 424854..426086 (-) 1233 WP_284060609.1 MFS transporter -
  ODS73_RS02325 (ODS73_02325) - 426129..426716 (-) 588 WP_016397727.1 lanthionine synthetase LanC family protein -
  ODS73_RS02330 (ODS73_02330) - 426616..427005 (-) 390 WP_016397728.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=737533 ODS73_RS02305 WP_000518011.1 421970..422659(+) (covR) [Streptococcus pneumoniae strain BM6001]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=737533 ODS73_RS02305 WP_000518011.1 421970..422659(+) (covR) [Streptococcus pneumoniae strain BM6001]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467