Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   P9N54_RS01895 Genome accession   NZ_CP121294
Coordinates   355984..356640 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O155:H21 strain NWU_1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 350984..361640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P9N54_RS01865 (P9N54_01865) yecA 352235..352900 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  P9N54_RS01885 (P9N54_01885) pgsA 353550..354098 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  P9N54_RS01890 (P9N54_01890) uvrC 354155..355987 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  P9N54_RS01895 (P9N54_01895) letA 355984..356640 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  P9N54_RS23460 - 356782..356853 (+) 72 Protein_375 transcriptional regulator -
  P9N54_RS01900 (P9N54_01900) yecU 356936..357112 (+) 177 WP_000590347.1 protein YecU -
  P9N54_RS01905 (P9N54_01905) yecF 357099..357323 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  P9N54_RS01910 (P9N54_01910) sdiA 357390..358112 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  P9N54_RS01915 (P9N54_01915) tcyN 358342..359094 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  P9N54_RS01920 (P9N54_01920) tcyL 359091..359759 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  P9N54_RS01925 (P9N54_01925) dcyD 359774..360760 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=736814 P9N54_RS01895 WP_000611335.1 355984..356640(-) (letA) [Escherichia coli O155:H21 strain NWU_1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=736814 P9N54_RS01895 WP_000611335.1 355984..356640(-) (letA) [Escherichia coli O155:H21 strain NWU_1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486