Detailed information NTG0736368

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: P6H83_RS22450
• Genome accession: NZ_CP121199
• Coordinates: 4652776..4653801 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain E50
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4647776..4658801

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P6H83_RS22430 (P6H83_22430)	metJ	4648961..4649278 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
P6H83_RS22435 (P6H83_22435)	yiiX	4649338..4649946 (+)	609	WP_000702307.1	YiiX family permuted papain-like enzyme	-
P6H83_RS22440 (P6H83_22440)	rpmE	4650007..4650219 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
P6H83_RS22445 (P6H83_22445)	priA	4650422..4652620 (+)	2199	WP_001361702.1	primosomal protein N'	Machinery gene
P6H83_RS22450 (P6H83_22450)	cytR	4652776..4653801 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
P6H83_RS22455 (P6H83_22455)	ftsN	4653893..4654852 (+)	960	WP_000068841.1	cell division protein FtsN	-
P6H83_RS22460 (P6H83_22460)	hslV	4654945..4655475 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
P6H83_RS22465 (P6H83_22465)	hslU	4655485..4656816 (+)	1332	WP_001293340.1	HslU--HslV peptidase ATPase subunit	-
P6H83_RS22470 (P6H83_22470)	menA	4656883..4657809 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
P6H83_RS22475 (P6H83_22475)	rraA	4657902..4658387 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=736368 P6H83_RS22450 WP_000644904.1 4652776..4653801(+) (cytR) [Escherichia coli strain E50]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=736368 P6H83_RS22450 WP_000644904.1 4652776..4653801(+) (cytR) [Escherichia coli strain E50]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGACCCT
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTACCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGTTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCAATGCAACAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGTCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGATTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628