Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   P8R99_RS11665 Genome accession   NZ_CP121160
Coordinates   2241827..2243608 (-) Length   593 a.a.
NCBI ID   WP_001003967.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain S5     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2236827..2248608
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8R99_RS11640 rplJ 2238898..2239398 (+) 501 WP_001287288.1 50S ribosomal protein L10 -
  P8R99_RS11645 rplL 2239462..2239827 (+) 366 WP_001196973.1 50S ribosomal protein L7/L12 -
  P8R99_RS11650 - 2240033..2240713 (-) 681 WP_001015311.1 IS6-like element IS1216 family transposase -
  P8R99_RS11655 - 2240855..2241535 (-) 681 WP_001015311.1 IS6-like element IS1216 family transposase -
  P8R99_RS11660 - 2241594..2241785 (+) 192 Protein_2222 glycerophosphodiester phosphodiesterase -
  P8R99_RS11665 uvrC 2241827..2243608 (-) 1782 WP_001003967.1 excinuclease ABC subunit UvrC Machinery gene
  P8R99_RS11670 - 2243768..2244535 (+) 768 WP_000567588.1 epoxyqueuosine reductase QueH -
  P8R99_RS11675 - 2244594..2245934 (-) 1341 WP_000285042.1 MATE family efflux transporter -
  P8R99_RS11680 - 2246034..2246450 (-) 417 WP_000245060.1 VOC family protein -
  P8R99_RS11685 - 2246454..2246951 (-) 498 WP_000582585.1 hypothetical protein -
  P8R99_RS11690 - 2247181..2247777 (+) 597 WP_000162273.1 Ltp family lipoprotein -
  P8R99_RS11695 - 2248032..2248565 (-) 534 WP_001042297.1 hypothetical protein -

Sequence

Protein


Download         Length: 593 a.a.        Molecular weight: 68357.86 Da        Isoelectric Point: 9.5360

>NTDB_id=736294 P8R99_RS11665 WP_001003967.1 2241827..2243608(-) (uvrC) [Streptococcus agalactiae strain S5]
MNELIKHKLELLPDSPGCYLHKDKNGTIIYVGKAKNLKNRVRSYFHGSHNTKTELLVSEIEDFEYIVTTSNTEALLLEIN
LIQENMPKYNIRLKDDKSYPYIKITNERYPRLMITRQVKKSDGTYFGPYPDSGAATEIKRLLDRLFPFKKCTNPANKVCF
YYHLGQCNAHTVCQTNKAYWDSLREDVKQFLNGKDNKIVNGLTEKMKSAAMTMEFERAAEYRDLIEAISLLRTKQRVIHQ
DMKDRDVFGYFVDKGWMCVQVFFVRNGKLIQRDVNMFPYYNEPEEDFLTYIGQFYQDTKHFLPKEVFIPQDIDAKSVETI
VGCKIVKPQRGEKKQLVNLAIKNARVSLQQKFDLLEKDIRKTHGAIENLGNLLNIPKPVRIEAFDNSNIQGTSPVAAMVV
FVNGKPSKKDYRKFKIKTVIGPDDYASMREVIHRRYSRVLKDGLTPPDLIVIDGGQGQVNIARDVIENQLGLAIPIAGLQ
KNDKHQTHELLFGDPLEVVELPRNSEEFFLLHRIQDEVHRFAITFHRQLRSKNSFSSKLDGITGLGPKRKQLLMKHFKSL
PSIQKADIEDIIMCGIPRNVAESLRDSLNDPPK

Nucleotide


Download         Length: 1782 bp        

>NTDB_id=736294 P8R99_RS11665 WP_001003967.1 2241827..2243608(-) (uvrC) [Streptococcus agalactiae strain S5]
ATGAATGAACTGATTAAACATAAGCTAGAATTGTTACCAGACAGTCCTGGTTGTTACCTTCATAAAGATAAGAATGGGAC
AATTATTTATGTAGGTAAGGCTAAAAATCTTAAGAATCGTGTGAGAAGTTATTTTCATGGGAGTCATAATACTAAGACAG
AACTTTTGGTCTCTGAGATTGAAGACTTTGAATACATTGTGACAACATCTAATACCGAAGCTCTATTATTGGAAATTAAT
TTAATCCAAGAAAATATGCCGAAGTATAATATTCGATTGAAAGATGATAAGTCTTACCCATATATCAAAATAACAAATGA
ACGTTATCCTCGTCTTATGATTACACGTCAAGTAAAAAAATCAGATGGCACTTATTTTGGACCTTATCCGGATTCTGGGG
CAGCAACTGAGATTAAGCGGTTACTAGATAGGCTCTTTCCTTTTAAGAAATGTACTAATCCAGCAAATAAAGTATGCTTT
TATTATCATTTAGGGCAATGCAATGCACATACAGTTTGTCAAACTAATAAAGCTTATTGGGATAGTCTGAGAGAAGATGT
AAAACAGTTTCTTAATGGTAAAGATAATAAAATTGTTAACGGATTAACTGAAAAAATGAAGAGCGCTGCTATGACTATGG
AATTTGAGCGTGCGGCTGAATATCGAGATTTGATCGAAGCAATTAGTTTGTTGCGTACTAAGCAGCGTGTTATTCATCAA
GATATGAAGGATAGAGATGTTTTTGGTTATTTCGTTGATAAGGGTTGGATGTGTGTACAGGTCTTTTTTGTTCGAAATGG
AAAATTGATTCAGCGTGACGTGAATATGTTTCCTTATTATAATGAACCAGAGGAAGATTTTCTAACTTACATAGGGCAAT
TTTATCAAGATACAAAACATTTTCTACCCAAAGAAGTCTTTATTCCACAGGATATTGATGCTAAGTCGGTTGAAACAATT
GTAGGCTGTAAGATTGTTAAACCACAACGTGGTGAAAAGAAACAGTTAGTAAATCTGGCAATAAAAAATGCTCGTGTCAG
TTTACAACAGAAGTTTGACTTACTGGAAAAAGATATTCGTAAAACTCATGGGGCAATTGAAAATTTAGGTAATCTTCTTA
ATATCCCTAAACCAGTACGCATAGAAGCATTTGATAATTCCAATATTCAAGGGACAAGTCCAGTAGCTGCTATGGTGGTA
TTTGTGAATGGAAAGCCAAGTAAAAAAGACTATCGAAAGTTTAAAATTAAGACTGTTATCGGACCAGATGATTATGCTAG
TATGAGAGAAGTCATTCATCGGCGTTATAGTAGGGTTTTAAAAGATGGCTTGACACCTCCGGACTTGATTGTAATTGATG
GTGGTCAGGGGCAAGTAAATATAGCGCGTGATGTTATTGAGAACCAATTAGGTTTAGCCATACCTATTGCAGGTTTGCAA
AAGAATGATAAACACCAAACACATGAATTACTTTTTGGAGATCCTTTAGAAGTAGTAGAACTACCGCGTAATTCAGAAGA
ATTTTTCTTACTTCACCGTATTCAAGATGAGGTACATCGTTTTGCTATTACTTTTCATCGTCAATTACGCTCCAAAAATT
CCTTTTCTTCAAAATTAGATGGTATCACTGGGTTGGGACCAAAACGTAAACAATTGCTAATGAAACATTTTAAAAGCTTA
CCTAGTATCCAAAAAGCTGATATTGAGGACATTATTATGTGTGGTATTCCTAGGAATGTAGCAGAAAGTCTCCGAGATTC
TCTTAATGATCCTCCTAAATAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

UvrB/uvrC motif (UVR)

(197-229)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.74

99.325

0.762
  uvrC Streptococcus pneumoniae R6

76.401

99.325

0.759
  uvrC Streptococcus pneumoniae D39

76.401

99.325

0.759