Detailed information NTG0736268

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: P8R99_RS09180
• Genome accession: NZ_CP121160
• Coordinates: 1742203..1742664 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874060.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain S5
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1737203..1747664

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P8R99_RS09150	-	1738819..1739184 (+)	366	WP_000285373.1	DUF1033 family protein	-
P8R99_RS09155	comGA	1739356..1740327 (+)	972	WP_000250799.1	competence type IV pilus ATPase ComGA	Machinery gene
P8R99_RS09160	comGB	1740221..1741264 (+)	1044	WP_228322108.1	competence type IV pilus assembly protein ComGB	Machinery gene
P8R99_RS09165	comGC/cglC	1741261..1741590 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
P8R99_RS09170	comGD	1741565..1741978 (+)	414	WP_017646959.1	competence type IV pilus minor pilin ComGD	Machinery gene
P8R99_RS09175	comGE	1741950..1742249 (+)	300	WP_025195478.1	competence type IV pilus minor pilin ComGE	Machinery gene
P8R99_RS09180	comGF	1742203..1742664 (+)	462	WP_001874060.1	competence type IV pilus minor pilin ComGF	Machinery gene
P8R99_RS09185	comGG	1742642..1743013 (+)	372	WP_000601103.1	competence type IV pilus minor pilin ComGG	Machinery gene
P8R99_RS09190	comGH	1743128..1744102 (+)	975	WP_001008568.1	class I SAM-dependent methyltransferase	Machinery gene
P8R99_RS09195	-	1744134..1745327 (+)	1194	WP_000047537.1	acetate kinase	-
P8R99_RS09200	-	1745479..1745685 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
P8R99_RS09205	-	1745744..1745881 (+)	138	WP_079263416.1	hypothetical protein	-
P8R99_RS09210	-	1745984..1746376 (+)	393	WP_001265365.1	hypothetical protein	-
P8R99_RS09215	-	1746445..1747110 (+)	666	WP_000008107.1	type II CAAX endopeptidase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17861.86 Da
• Isoelectric Point: 9.8392

>NTDB_id=736268 P8R99_RS09180 WP_001874060.1 1742203..1742664(+) (comGF) [Streptococcus agalactiae strain S5]
MKVIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=736268 P8R99_RS09180 WP_001874060.1 1742203..1742664(+) (comGF) [Streptococcus agalactiae strain S5]
TTGAAGGTAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATTACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAAACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373