Detailed information NTG0736245

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: P8R99_RS07545
• Genome accession: NZ_CP121160
• Coordinates: 1409881..1412457 (+)
• Length: 858 a.a.
• NCBI ID: WP_001118381.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain S5
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1404881..1417457

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P8R99_RS07520	-	1405127..1406071 (+)	945	WP_000857770.1	YitT family protein	-
P8R99_RS07525	-	1406179..1407051 (+)	873	WP_000915473.1	YitT family protein	-
P8R99_RS07530	-	1407078..1407386 (-)	309	WP_001138861.1	bacteriocin immunity protein	-
P8R99_RS07535	argS	1407474..1409165 (-)	1692	WP_000379864.1	arginine--tRNA ligase	-
P8R99_RS07540	argR	1409387..1409824 (+)	438	WP_001033152.1	arginine repressor	-
P8R99_RS07545	hexA	1409881..1412457 (+)	2577	WP_001118381.1	DNA mismatch repair protein MutS	Machinery gene
P8R99_RS07550	-	1412514..1412717 (-)	204	WP_000191849.1	cold shock domain-containing protein	-
P8R99_RS07555	hexB	1412943..1414916 (+)	1974	WP_000034615.1	DNA mismatch repair endonuclease MutL	Machinery gene
P8R99_RS07560	-	1414948..1416180 (+)	1233	WP_000657478.1	MFS transporter	-
P8R99_RS07565	ruvA	1416182..1416772 (+)	591	WP_000272490.1	Holliday junction branch migration protein RuvA	Machinery gene
P8R99_RS07570	-	1416795..1417346 (+)	552	WP_000817341.1	DNA-3-methyladenine glycosylase I	-

Sequence

Protein

• Length: 858 a.a.
• Molecular weight: 97069.74 Da
• Isoelectric Point: 4.9042

>NTDB_id=736245 P8R99_RS07545 WP_001118381.1 1409881..1412457(+) (hexA) [Streptococcus agalactiae strain S5]
MAKPTISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNAEKPIPMAGVPYHSAQQYIDVLV
ELGYKVAIAEQMEDPKKAVGVVKREVVQVVTPGTVVESTKPDSANNFLVAIDSQDQQTFGLAYMDVSTGEFQATLLTDFE
SVRSEILNLKAREIVVGYQLTDEKNHLLTKQMNLLLSYEDERLNDIHLIDEQLTDLEISAAEKLLQYVHRTQKRELSHLQ
KVVHYEIKDYLQMSYATKNSLDLLENARTSKKHGSLYWLLDETKTAMGTRMLRTWIDRPLVSMNRIKERQDIIQVFLDYF
FERNDLTESLKGVYDIERLASRVSFGKANPKDLLQLGRTLSQIPRIKMILQSFNQPELDIVVNKIDTMPELESLINTAIA
PEAQTTITEGNIIKSGFDKQLDNYRTVMREGTGWIADIEAKERAASGIGTLKIDYNKKDGYYFHVTNSNLSLVPEHFFRK
ATLKNSERYGTAELAKIEGEMLEAREQSSNLEYDIFMRVRAQVESYIKRLQELAKTIATVDVLQSLAVVAENHHYVRPKF
NDEHQIKIKNGRHATVEKVMGVQEYIPNSIYFDSQTDIQLITGPNMSGKSTYMRQLALTVIMAQMGGFVSADEVDLPVFD
AIFTRIGAADDLISGQSTFMVEMMEANQAVKRASDKSLILFDELGRGTATYDGMALAQSIIEYIHDRVRAKTMFATHYHE
LTDLSEQLTRLVNVHVATLERDGEVTFLHKIEPGPADKSYGIHVAKIAGLPIDLLDRATDILSQLEADAVQLIVSAPQEA
VTADLNEELDPGKQQGQLSLFEEHSNAGRVIEELEAIDIMNLTPMQAMNAIFDLKKLL

Nucleotide

• Length: 2577 bp

>NTDB_id=736245 P8R99_RS07545 WP_001118381.1 1409881..1412457(+) (hexA) [Streptococcus agalactiae strain S5]
ATGGCCAAGCCAACGATATCACCGGGAATGCAACAGTATCTGGATATAAAAGAGAATTATCCAGATGCTTTTTTGCTTTT
TAGAATGGGTGATTTTTATGAATTATTTTATGATGATGCGGTAAAAGCAGCACAAATCCTGGAAATTAGCTTGACTAGTC
GAAATAAGAACGCAGAAAAGCCAATCCCAATGGCAGGAGTTCCCTATCACTCAGCTCAACAGTATATTGACGTTTTAGTT
GAATTAGGTTACAAAGTAGCCATTGCTGAGCAGATGGAAGATCCTAAAAAAGCTGTGGGAGTGGTCAAGCGTGAGGTAGT
GCAAGTTGTTACCCCAGGAACGGTTGTGGAGTCAACGAAGCCGGATAGTGCTAATAATTTCTTAGTAGCGATTGATTCGC
AAGATCAACAAACATTTGGTCTAGCATATATGGATGTCTCAACTGGAGAGTTTCAGGCAACCCTTTTAACAGATTTTGAG
TCCGTCCGTAGTGAAATACTAAATTTAAAAGCTCGTGAGATTGTAGTAGGATATCAATTGACGGACGAAAAAAATCACCT
ACTGACGAAGCAGATGAACTTGCTTTTGTCATACGAAGACGAACGACTTAATGATATTCATTTGATTGATGAGCAGTTAA
CTGATTTGGAAATATCTGCTGCGGAAAAACTTTTACAATATGTGCATAGAACACAAAAGCGTGAACTTAGTCATTTACAG
AAAGTAGTTCATTATGAAATAAAGGACTATTTACAAATGTCATATGCAACGAAAAATAGTCTAGATTTACTGGAGAATGC
TAGAACAAGCAAGAAGCATGGAAGTCTTTACTGGTTGTTAGATGAGACTAAAACAGCGATGGGAACTCGAATGCTGAGAA
CTTGGATTGACAGGCCTTTGGTAAGTATGAATCGAATCAAGGAACGTCAAGATATTATTCAAGTGTTTCTTGATTATTTT
TTTGAGAGAAACGATCTCACAGAAAGTTTAAAGGGTGTATATGATATTGAACGCCTAGCAAGTCGAGTATCTTTCGGAAA
AGCCAACCCTAAAGATCTATTGCAACTCGGACGGACCTTATCACAAATTCCTCGGATTAAAATGATTTTACAGTCCTTCA
ATCAACCTGAGCTTGACATTGTTGTCAACAAGATTGACACTATGCCTGAATTAGAAAGTTTAATTAATACGGCGATAGCC
CCAGAAGCACAGACTACTATCACTGAGGGAAACATTATCAAGTCTGGGTTTGATAAGCAATTGGATAATTATCGAACAGT
GATGCGTGAAGGTACAGGTTGGATTGCTGATATTGAAGCTAAGGAAAGAGCAGCAAGTGGTATCGGTACCCTTAAAATTG
ATTATAATAAAAAAGACGGCTATTACTTCCATGTGACCAATTCCAATTTATCACTAGTACCGGAGCATTTTTTCCGTAAA
GCGACATTAAAAAATTCTGAACGCTATGGAACAGCAGAACTAGCCAAAATTGAAGGTGAAATGCTCGAAGCTCGCGAGCA
ATCTTCAAATTTAGAATATGATATTTTTATGCGTGTTCGTGCTCAAGTAGAATCTTATATTAAACGTCTTCAAGAGTTAG
CAAAGACTATTGCAACCGTTGATGTTCTACAGAGTTTGGCAGTAGTTGCAGAAAATCATCACTATGTTCGTCCCAAATTT
AATGATGAACATCAGATTAAGATTAAGAATGGGCGTCATGCAACCGTTGAAAAAGTGATGGGAGTGCAAGAATATATTCC
CAATAGTATCTATTTTGATAGTCAGACAGATATCCAGTTGATTACAGGACCAAATATGAGTGGTAAGTCGACCTATATGC
GCCAGTTAGCTTTGACAGTTATTATGGCACAAATGGGAGGTTTTGTATCGGCAGACGAAGTTGATTTGCCTGTATTTGAT
GCAATATTTACTAGGATTGGTGCTGCTGATGACTTAATTTCTGGGCAATCAACCTTTATGGTAGAAATGATGGAAGCGAA
TCAGGCTGTAAAACGAGCCAGTGATAAATCTTTGATTCTTTTTGATGAATTAGGTCGAGGGACAGCCACTTATGATGGTA
TGGCATTAGCTCAATCGATTATAGAATATATTCATGACCGTGTTAGGGCAAAAACAATGTTTGCAACTCATTACCATGAG
TTGACAGATTTATCTGAACAATTGACAAGGCTTGTCAATGTACACGTGGCTACTTTAGAGAGAGATGGAGAAGTTACCTT
CTTACATAAAATTGAACCTGGACCTGCGGACAAGTCTTATGGGATACACGTCGCAAAAATAGCTGGTTTACCAATTGACT
TATTGGATAGGGCAACTGATATTTTATCACAGTTGGAAGCTGATGCAGTACAGTTGATCGTATCAGCCCCCCAAGAAGCT
GTTACTGCTGACTTAAATGAGGAACTAGATCCTGGGAAGCAACAAGGACAATTATCGCTTTTTGAAGAACATTCAAATGC
AGGTAGGGTTATTGAGGAGTTAGAAGCGATAGATATAATGAATCTAACTCCAATGCAAGCTATGAATGCTATATTTGATT
TAAAGAAATTATTATAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (416-506)

• MutS domain II (MutS_II) (126-240)

• MutS domain V (MutS_V) (600-786)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (257-547)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	69.338	100	0.696
mutS	Pseudomonas stutzeri strain ATCC 17587	36.644	100	0.374