Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   P8R98_RS10580 Genome accession   NZ_CP121159
Coordinates   2146553..2147194 (-) Length   213 a.a.
NCBI ID   WP_000357891.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain S1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2141553..2152194
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P8R98_RS10555 - 2141953..2142936 (-) 984 WP_000764456.1 sugar-binding transcriptional regulator -
  P8R98_RS10560 - 2143055..2143810 (-) 756 WP_001080746.1 DeoR family transcriptional regulator -
  P8R98_RS10565 - 2143931..2144707 (+) 777 WP_000180536.1 glycyl-radical enzyme activating protein -
  P8R98_RS10570 - 2144753..2145109 (-) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -
  P8R98_RS10575 - 2145111..2146511 (-) 1401 WP_000339135.1 Cof-type HAD-IIB family hydrolase -
  P8R98_RS10580 vraR 2146553..2147194 (-) 642 WP_000357891.1 response regulator transcription factor Regulator
  P8R98_RS10585 - 2147187..2148206 (-) 1020 WP_278043459.1 sensor histidine kinase -
  P8R98_RS10590 liaF 2148203..2148898 (-) 696 WP_000714456.1 cell wall-active antibiotics response protein LiaF -
  P8R98_RS10595 pknB 2149058..2151013 (-) 1956 WP_000614565.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  P8R98_RS10600 - 2151013..2151750 (-) 738 WP_000406233.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23634.35 Da        Isoelectric Point: 5.0159

>NTDB_id=736163 P8R98_RS10580 WP_000357891.1 2146553..2147194(-) (vraR) [Streptococcus agalactiae strain S1]
MDKIKIVLVDDHEMVRLGLKSFLNLQADVEVIGEASNGLEGIKKALELRPDVVVMDLVMPEMDGVEATLALLKDWPEAAI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIRKVARGEQAIENEVDKKIKAHDKCPALHEGLTARERDILNLLA
KGYDNQRIADELFISLKTVKTHVSNILGKLNVADRTQAVVYAFQHHLVPQDDE

Nucleotide


Download         Length: 642 bp        

>NTDB_id=736163 P8R98_RS10580 WP_000357891.1 2146553..2147194(-) (vraR) [Streptococcus agalactiae strain S1]
ATGGATAAAATAAAAATTGTACTTGTTGATGACCATGAGATGGTTCGTCTCGGTTTAAAAAGTTTTTTAAACTTACAAGC
TGATGTTGAAGTAATAGGTGAAGCCTCAAATGGTTTAGAAGGCATAAAAAAAGCCCTGGAGTTACGTCCAGACGTTGTTG
TTATGGATTTAGTAATGCCTGAAATGGATGGTGTAGAAGCAACCTTAGCATTATTGAAGGATTGGCCAGAAGCTGCTATT
TTAGTCTTAACATCTTACTTGGATAATGAAAAAATTTACCCTGTTATTGAAGCAGGTGCCAAAGGCTATATGTTAAAGAC
CTCAAGCGCAGCAGAGATTCTTAATGCCATTCGTAAAGTTGCAAGGGGAGAACAAGCTATTGAAAATGAAGTAGATAAGA
AAATTAAGGCTCATGATAAATGTCCAGCTTTACATGAGGGCTTAACAGCAAGGGAACGTGATATTCTTAATTTATTAGCC
AAAGGTTATGACAATCAAAGGATTGCTGATGAATTATTTATCTCGTTAAAGACTGTTAAAACTCATGTTTCTAATATTTT
GGGAAAACTAAATGTAGCAGATCGAACTCAAGCAGTTGTATATGCTTTCCAACACCATTTGGTACCACAAGATGATGAAT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

96.714

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.394