Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   P6H86_RS13485 Genome accession   NZ_CP121157
Coordinates   2756933..2757589 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain E89     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2751933..2762589
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P6H86_RS13455 (P6H86_13455) - 2753063..2753803 (+) 741 Protein_2630 hypothetical protein -
  P6H86_RS13475 (P6H86_13475) pgsA 2754499..2755047 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  P6H86_RS13480 (P6H86_13480) uvrC 2755104..2756936 (-) 1833 WP_032187456.1 excinuclease ABC subunit UvrC Machinery gene
  P6H86_RS13485 (P6H86_13485) letA 2756933..2757589 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  P6H86_RS24480 - 2757731..2757847 (+) 117 WP_001302039.1 hypothetical protein -
  P6H86_RS13490 (P6H86_13490) yecU 2757885..2758061 (+) 177 WP_000590344.1 protein YecU -
  P6H86_RS13495 (P6H86_13495) yecF 2758048..2758272 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  P6H86_RS13500 (P6H86_13500) sdiA 2758340..2759062 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  P6H86_RS13505 (P6H86_13505) tcyN 2759292..2760044 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  P6H86_RS13510 (P6H86_13510) tcyL 2760041..2760709 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  P6H86_RS13515 (P6H86_13515) dcyD 2760724..2761710 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=736045 P6H86_RS13485 WP_000611335.1 2756933..2757589(-) (letA) [Escherichia coli strain E89]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=736045 P6H86_RS13485 WP_000611335.1 2756933..2757589(-) (letA) [Escherichia coli strain E89]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486