Detailed information NTG0735870

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: P6H84_RS08925
• Genome accession: NZ_CP121153
• Coordinates: 1845967..1848243 (+)
• Length: 758 a.a.
• NCBI ID: WP_000934036.1
• Uniprot ID: -
• Organism: Escherichia coli strain E57
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1840967..1853243

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
P6H84_RS08900 (P6H84_08900)	macA	1841938..1843053 (+)	1116	WP_000746460.1	macrolide transporter subunit MacA	-
P6H84_RS08905 (P6H84_08905)	macB	1843050..1844996 (+)	1947	WP_000188136.1	macrolide ABC transporter ATP-binding protein/permease MacB	-
P6H84_RS08910 (P6H84_08910)	cspD	1845069..1845293 (-)	225	WP_000410785.1	cold shock-like protein CspD	-
P6H84_RS08915 (P6H84_08915)	yljB	1845443..1845517 (+)	75	WP_001406719.1	protein YljB	-
P6H84_RS08920 (P6H84_08920)	clpS	1845616..1845936 (+)	321	WP_000520781.1	ATP-dependent Clp protease adapter ClpS	-
P6H84_RS08925 (P6H84_08925)	clpC	1845967..1848243 (+)	2277	WP_000934036.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
P6H84_RS08935 (P6H84_08935)	infA	1848868..1849086 (-)	219	WP_001040187.1	translation initiation factor IF-1	-
P6H84_RS08940 (P6H84_08940)	aat	1849370..1850074 (-)	705	WP_001241678.1	leucyl/phenylalanyl-tRNA--protein transferase	-
P6H84_RS08945 (P6H84_08945)	cydC	1850116..1851837 (-)	1722	WP_061092629.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-

Sequence

Protein

• Length: 758 a.a.
• Molecular weight: 84192.90 Da
• Isoelectric Point: 6.2512

>NTDB_id=735870 P6H84_RS08925 WP_000934036.1 1845967..1848243(+) (clpC) [Escherichia coli strain E57]
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQP
TLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVM
ADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIG
STTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAID
VIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAG
LGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAV
LLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEF
RNRLDNIIWFDHLSSDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANEL
LFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH

Nucleotide

• Length: 2277 bp

>NTDB_id=735870 P6H84_RS08925 WP_000934036.1 1845967..1848243(+) (clpC) [Escherichia coli strain E57]
ATGCTCAATCAAGAACTGGAACTCAGTTTAAATATGGCTTTCGCCAGAGCGCGCGAGCACCGTCATGAGTTTATGACCGT
CGAGCACTTGTTACTGGCGCTGCTCAGTAACCCATCTGCCCGGGAGGCGCTGGAAGCGTGTTCTGTGGATTTGGTTGCGC
TCCGTCAGGAACTGGAAGCCTTTATTGAACAAACCACACCCGTTCTGCCTGCCAGTGAAGAGGAGCGCGACACACAGCCG
ACGCTGAGTTTTCAGCGTGTACTGCAACGTGCGGTCTTCCATGTCCAGTCCTCCGGTCGCAATGAGGTTACCGGTGCAAA
CGTTTTGGTCGCTATCTTTAGCGAACAGGAGTCGCAGGCGGCATATCTGTTGCGTAAACATGAAGTCAGCCGTCTCGATG
TGGTGAACTTTATCTCTCATGGCACGCGTAAAGACGAGCCGACACAGTCTTCTGATCCTGGCAGCCAGCCAAACAGCGAA
GAACAAGCTGGTGGGGAGGAACGTATGGAGAATTTCACGACGAACCTGAATCAGCTTGCGCGAGTGGGCGGAATCGACCC
ACTGATTGGTCGTGAGAAGGAGCTGGAGCGTGCTATTCAGGTTCTCTGCCGTCGCCGTAAAAACAACCCGCTGCTGGTGG
GGGAGTCTGGTGTCGGTAAAACCGCGATTGCGGAAGGTCTTGCCTGGCGAATTGTTCAGGGCGATGTGCCGGAAGTGATG
GCTGACTGTACGATTTACTCTCTCGATATCGGTTCTCTGTTAGCGGGCACAAAATATCGCGGCGACTTTGAAAAACGTTT
TAAAGCGTTGCTCAAGCAGCTGGAGCAGGACACTAACAGCATCCTGTTTATTGATGAGATCCACACCATTATCGGTGCGG
GTGCAGCGTCTGGTGGCCAGGTCGATGCGGCTAACCTGATCAAACCGCTGCTCTCCAGCGGTAAAATTCGCGTAATTGGT
TCGACAACCTATCAGGAGTTCAGCAACATTTTCGAGAAAGACCGTGCTCTGGCGCGTCGCTTCCAGAAAATTGATATTAC
TGAACCGTCGATCGAAGAAACTGTTCAAATCATCAATGGCCTGAAACCGAAGTATGAAGCGCACCACGACGTGCGTTATA
CCGCAAAAGCGGTGCGTGCGGCGGTAGAGTTGGCGGTGAAATACATTAACGATCGTCATCTGCCGGATAAAGCGATTGAT
GTTATCGACGAAGCGGGCGCTCGCGCGCGTCTGATGCCGGTCAGCAAACGCAAGAAAACCGTTAATGTGGCGGATATTGA
GTCCGTGGTGGCCCGTATTGCACGCATTCCAGAGAAGAGTGTTTCTCAGAGTGACCGCGATACCCTGAAAAACCTCGGCG
ATCGCCTGAAAATGCTGGTCTTCGGTCAGGATAAAGCCATTGAGGCGCTGACTGAAGCCATTAAGATGGCGCGTGCAGGT
TTAGGTCACGAACATAAACCGGTCGGTTCGTTCCTGTTTGCCGGCCCTACCGGGGTCGGGAAAACAGAGGTGACGGTACA
GCTTTCGAAAGCTTTGGGCATTGAGCTTCTGCGCTTTGATATGTCCGAGTATATGGAACGCCATACCGTCAGCCGTCTGA
TTGGTGCACCTCCGGGATACGTTGGTTTTGATCAGGGCGGTTTGCTGACTGATGCGGTCATCAAGCATCCACATGCGGTG
CTGCTGCTGGACGAAATCGAGAAAGCGCACCCGGACGTGTTCAATATTCTGTTGCAGGTGATGGACAACGGTACGCTGAC
CGATAACAACGGACGTAAAGCGGACTTCCGTAACGTGGTATTGGTGATGACCACCAACGCTGGGGTACGAGAAACTGAGC
GTAAATCGATTGGTCTTATCCACCAGGACAACAGTACCGATGCGATGGAAGAGATCAAGAAGATCTTTACGCCGGAGTTT
CGTAACCGTCTCGACAACATTATCTGGTTCGATCATCTCTCCTCCGACGTGATCCATCAGGTAGTGGATAAATTCATCGT
CGAGTTGCAGGTTCAGCTGGATCAGAAAGGTGTTTCTCTGGAAGTGAGCCAGGAAGCGCGTAACTGGCTGGCCGAGAAAG
GTTACGACCGGGCAATGGGCGCACGTCCGATGGCGCGTGTCATCCAGGACAACCTGAAAAAACCGCTCGCCAACGAACTG
TTGTTTGGTTCGCTGGTGGACGGCGGTCAGGTGACGGTTGCGCTGGATAAAGAGAAAAATGAGCTGACTTATGGATTCCA
GAGTGCACAAAAGCACAAGGCGGAAGCAGCGCATTAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (653-733)

• AAA domain (Cdc48 subfamily) (AAA_2) (486-647)

• AAA lid domain (AAA_lid_9) (350-452)

• ATPase family associated with various cellular activities (AAA) (AAA) (211-342)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (13-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	38.868	100	0.408
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.346	96.042	0.397
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	35.583	100	0.383
clpC	Streptococcus thermophilus LMD-9	42.37	89.05	0.377
clpC	Streptococcus thermophilus LMG 18311	42.222	89.05	0.376
clpC	Streptococcus mutans UA159	39.407	93.404	0.368
clpC	Streptococcus pneumoniae TIGR4	42.59	84.565	0.36
clpC	Streptococcus pneumoniae Rx1	42.59	84.565	0.36
clpC	Streptococcus pneumoniae D39	42.59	84.565	0.36