Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   FNL83_RS00190 Genome accession   NZ_AP019721
Coordinates   39293..40654 (-) Length   453 a.a.
NCBI ID   WP_001631036.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain NBRC 100911     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 37668..56519 39293..40654 within 0


Gene organization within MGE regions


Location: 37668..56519
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNL83_RS00185 (Sep02g_00320) ccrB 37668..39296 (-) 1629 WP_001631035.1 cassette chromosome recombinase CcrB Machinery gene
  FNL83_RS00190 (Sep02g_00330) ccrA 39293..40654 (-) 1362 WP_001631036.1 cassette chromosome recombinase CcrA Machinery gene
  FNL83_RS00195 (Sep02g_00340) - 40841..41470 (-) 630 Protein_34 hypothetical protein -
  FNL83_RS11975 (Sep02g_00350) - 41479..41817 (+) 339 Protein_35 recombinase family protein -
  FNL83_RS00205 (Sep02g_00370) - 41929..42288 (-) 360 WP_001631039.1 hypothetical protein -
  FNL83_RS00210 (Sep02g_00380) - 42495..42821 (+) 327 WP_000391495.1 ArsR/SmtB family transcription factor -
  FNL83_RS00220 (Sep02g_00390) - 43151..45076 (+) 1926 WP_002485723.1 heavy metal translocating P-type ATPase -
  FNL83_RS00225 - 46244..47149 (-) 906 Protein_39 transposase -
  FNL83_RS00230 (Sep02g_00400) - 47270..47839 (+) 570 WP_002470562.1 hypothetical protein -
  FNL83_RS00235 (Sep02g_00410) - 47884..49041 (+) 1158 WP_002485721.1 hypothetical protein -
  FNL83_RS00240 (Sep02g_00420) - 49224..49496 (+) 273 WP_002501902.1 hypothetical protein -
  FNL83_RS00245 (Sep02g_00430) - 49526..50200 (+) 675 WP_134943505.1 IS6-like element IS257 family transposase -
  FNL83_RS00250 (Sep02g_00440) lspA 50228..50680 (-) 453 WP_164071529.1 signal peptidase II -
  FNL83_RS00255 (Sep02g_00450) - 50840..51241 (+) 402 WP_057504659.1 ArsR/SmtB family transcription factor -
  FNL83_RS00260 (Sep02g_00460) - 51495..52262 (+) 768 WP_057504658.1 ZIP family metal transporter -
  FNL83_RS00265 (Sep02g_00480) - 52519..54927 (+) 2409 WP_002485759.1 heavy metal translocating P-type ATPase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 53316.45 Da        Isoelectric Point: 9.8596

>NTDB_id=73566 FNL83_RS00190 WP_001631036.1 39293..40654(-) (ccrA) [Staphylococcus epidermidis strain NBRC 100911]
MEEAIAYVRQSTLKQQSLATQKSLIMDTAKQYGWSNVAFYDDKKTGRHTKRSGYQKMVEIITSGKCKVLCCYRLNRLHRN
LKNAIQFFEICKKHHITIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTKNGIREKAKQGKLITTHAPFGYRYR
KGCFVVQEEEAYTVKSVYRWYLQGLGYKKISQHLDSNPNLIPRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIIDIDT
FEEAQERRIHKQLNRSNSRNKLKRRIKCPYCQSTLTNLTIKKENYSLRYYVCPKNMNDAYRTCPFKSINAPELESEVLDT
CKKYFEEQSFHKRLNNTILKVLKQQQMKHKETHLTQEQLIEKLAQNRIDVKTFKRLSASCKSEENYSTYSTYQIDDKLKY
VIKNKITLQDIAPFIDCIKITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=73566 FNL83_RS00190 WP_001631036.1 39293..40654(-) (ccrA) [Staphylococcus epidermidis strain NBRC 100911]
ATGGAAGAAGCGATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCTACTCAAAAATCGCTCATTATGGA
TACCGCTAAGCAATATGGATGGTCTAATGTGGCGTTTTATGATGATAAGAAAACAGGTCGACATACAAAACGTTCAGGTT
ATCAAAAAATGGTAGAAATAATTACGTCTGGAAAATGTAAAGTATTGTGTTGCTATCGCTTGAACCGACTACATCGTAAT
TTGAAAAATGCCATACAATTCTTTGAAATTTGTAAAAAGCATCACATCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGTTTGAACATACTTATGAGTCTAGCGGAAATGGAATCAAACAATATCAGCGAAC
AAACAAAAAATGGGATTAGAGAAAAAGCCAAACAAGGTAAGCTAATCACAACTCATGCTCCGTTTGGCTATCGTTATAGA
AAAGGTTGTTTTGTTGTACAAGAAGAAGAAGCGTATACAGTTAAATCGGTTTATCGCTGGTACTTACAAGGTCTAGGCTA
CAAAAAGATTTCCCAACATTTGGATAGTAATCCTAACCTTATTCCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGCGGTCGTGTCATCAATAAATATGGCACGTTTAATGATATCGTTCCACCTATTATTGATATTGATACA
TTTGAAGAAGCACAAGAGCGTCGTATTCATAAACAACTCAATCGATCCAATTCTAGAAATAAGCTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAGAACTATTCTCTACGTTACTATGTTTGTCCTA
AAAATATGAATGACGCTTATCGTACATGCCCATTTAAAAGTATCAATGCACCAGAACTTGAAAGTGAAGTGCTCGACACT
TGTAAAAAGTATTTTGAAGAACAATCGTTTCATAAACGATTGAATAACACAATACTCAAAGTCCTAAAACAGCAACAAAT
GAAGCATAAAGAAACCCATCTAACACAAGAACAACTTATCGAAAAGCTAGCTCAAAATCGTATTGATGTAAAAACGTTCA
AACGTTTATCTGCTAGTTGTAAAAGTGAAGAGAATTACTCTACTTATTCAACCTACCAAATCGATGACAAATTAAAATAT
GTCATAAAAAATAAAATAACTTTACAGGATATAGCACCTTTTATCGATTGCATCAAAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCACATTTAATAACTCCTGAAAGGAATGAAGTAATAT
GA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(168-248)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-322)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

54.628

97.792

0.534
  ccrA Staphylococcus aureus N315

50.564

97.792

0.494

Multiple sequence alignment