Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   OCL46_RS00265 Genome accession   NZ_CP106811
Coordinates   52720..55719 (-) Length   999 a.a.
NCBI ID   WP_317629300.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain 10531     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 38582..56681 52720..55719 within 0


Gene organization within MGE regions


Location: 38582..56681
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OCL46_RS00205 (OCL46_00205) orn 38961..39524 (-) 564 WP_003687260.1 oligoribonuclease -
  OCL46_RS00210 (OCL46_00210) prmA 39542..40429 (-) 888 WP_003692488.1 50S ribosomal protein L11 methyltransferase -
  OCL46_RS00215 (OCL46_00215) accC 40533..41894 (-) 1362 WP_033911172.1 acetyl-CoA carboxylase biotin carboxylase subunit -
  OCL46_RS00220 (OCL46_00220) accB 42008..42469 (-) 462 WP_003687267.1 acetyl-CoA carboxylase biotin carboxyl carrier protein -
  OCL46_RS00225 (OCL46_00225) - 42451..42708 (-) 258 WP_003687268.1 hypothetical protein -
  OCL46_RS00230 (OCL46_00230) queA 42825..43865 (+) 1041 WP_003687270.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  OCL46_RS00235 (OCL46_00235) carB 44066..47281 (-) 3216 WP_003699430.1 carbamoyl-phosphate synthase large subunit -
  OCL46_RS00240 (OCL46_00240) - 47292..47825 (-) 534 WP_003692498.1 hypothetical protein -
  OCL46_RS00245 (OCL46_00245) - 49108..49497 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  OCL46_RS00255 (OCL46_00255) - 49660..50039 (-) 380 Protein_48 VOC family protein -
  OCL46_RS00260 (OCL46_00260) carA 50093..51226 (-) 1134 WP_003699436.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  OCL46_RS00265 (OCL46_00265) pilC 52720..55719 (-) 3000 WP_317629300.1 PilC family type IV pilus tip adhesin Machinery gene
  OCL46_RS11755 pilC 55719..55841 (-) 123 WP_317629301.1 hypothetical protein Machinery gene

Sequence

Protein


Download         Length: 999 a.a.        Molecular weight: 109894.60 Da        Isoelectric Point: 9.8431

>NTDB_id=735553 OCL46_RS00265 WP_317629300.1 52720..55719(-) (pilC) [Neisseria gonorrhoeae strain 10531]
MNAQNQPEVKSNVPYSIKDKDRKRVFDYTSQKSSLGRTNNFISFNNNDEVVARKNGTAVFGTATYLPPYGKVSGFDADAL
KERANAVDWIRTTRPGLAGYAYTDVICRDAGQCPQLVYETKFAFGQQGLQRNGNKLDIYEDKSRDNSPIYKLKDYPWLGV
SFNLGSENTVKNGRSSGRLISSFSENNNNQTIVSTTRDRPISLGDRQREHTAVAYYLNAKLHLLDKKRIKDIAQGKTVDL
GTLRPRVETTGRNWLSYWATWKIEDKGNITVRLGLPEVKAGRCINKPNPNPKSALSPALTAPALWFGPVQNGKVQMYSAS
VSTYPGSSSSRIFLQELKTKTDPGRPGRHSLAALNERDIKSREPNFNSRQTVIRLPGGVYRIAPGNSGRVAGFNDNDGKN
DTFGIYKDRLVIPEPDEWSEVLLPWTARYYGNDDIFKTFNQPNNKKQSDKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPI
TAVGGYLATAANDGMVHLFKRNGTDQRGYELKLSYIPGTMPRQYFDNDTSALKDSTLAQELRTFAEKGYVGDRYGVDGGF
VLRRITDDQDRQKHFFMFGAMGLGGRGAYALDLTKIDNSNLTGVSMFDVKNESKNNGVKLGYTVGTPQIGKIRNGKYAAF
LASGYAAKDIVSSDNTTALYVYDLGNGGGSLIKKIEAPGGKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSGDNP
SKWTVRTIFQGTKPITSAPAVSRLADKRVVIFGTGSDLSEQDVVDKDQQYIYGIFDDDKGTVKVTVQNGTGGGLLEQVLK
EENKTLFLNKGSDGSGSKGWVVKLKEGQRVTVKPTVVLRTAFVTIRKYKDDGCGADTAILGINTADGGALTPRSARPIVP
EANKDVAQYSGHKTTSKGKSIPIGCMEKGGKTVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARN
NRCFSGKGVRTLLMNDLDSLDITGPMCGIKRLSWREVFF

Nucleotide


Download         Length: 3000 bp        

>NTDB_id=735553 OCL46_RS00265 WP_317629300.1 52720..55719(-) (pilC) [Neisseria gonorrhoeae strain 10531]
ATGAACGCGCAAAACCAGCCCGAGGTAAAGTCGAATGTGCCATATTCAATAAAGGACAAAGACAGGAAGCGGGTATTTGA
CTATACGAGCCAGAAAAGCAGCTTAGGCAGGACAAACAATTTTATCTCATTCAACAATAACGATGAAGTTGTTGCTCGAA
AAAACGGTACTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATGCCGACGCTCTG
AAAGAGCGCGCCAATGCCGTTGATTGGATTCGTACCACCCGGCCCGGGCTGGCAGGCTACGCCTACACCGACGTCATATG
CAGAGACGCAGGGCAATGCCCCCAACTTGTCTATGAGACCAAATTTGCCTTCGGTCAACAAGGGTTGCAAAGAAATGGCA
ACAAGCTGGATATATACGAAGACAAAAGCCGCGACAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTA
TCTTTCAATTTGGGCAGCGAGAATACCGTCAAAAATGGCAGATCATCCGGCAGATTGATATCTTCTTTTAGTGAAAACAA
TAATAATCAAACCATCGTCTCTACGACACGAGACCGCCCTATTTCCCTTGGCGACCGGCAGCGCGAACATACCGCCGTGG
CCTATTATCTGAACGCCAAGCTGCACCTGCTGGACAAAAAAAGGATTAAAGATATCGCCCAAGGCAAAACAGTGGATTTG
GGCACCTTGAGACCGCGCGTCGAGACGACAGGACGAAACTGGCTAAGTTATTGGGCTACGTGGAAGATTGAAGATAAAGG
GAACATTACAGTCCGCCTCGGCCTGCCGGAAGTCAAAGCAGGCCGCTGCATCAACAAACCGAACCCCAATCCCAAATCAG
CCCTTTCGCCGGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCG
GTTTCTACCTACCCCGGCAGTTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTAAAACCGACCCCGGCAGGCCCGG
CCGGCATTCCCTCGCCGCTTTGAATGAACGAGATATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTCATCC
GATTGCCGGGCGGCGTGTACCGGATCGCCCCGGGCAATAGCGGCCGGGTCGCGGGTTTTAATGACAATGACGGCAAAAAC
GACACTTTCGGCATCTACAAGGACAGGCTCGTCATACCTGAGCCCGACGAGTGGAGCGAAGTGCTGCTGCCTTGGACGGC
CCGGTATTACGGTAATGACGATATATTTAAAACATTCAACCAACCAAACAACAAAAAACAAAGCGACAAAAAACAATACA
GCCAAAAATACCGCATCCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATA
ACGGCGGTCGGCGGGTATCTGGCAACCGCCGCGAACGACGGGATGGTGCACCTGTTTAAAAGAAACGGCACAGACCAACG
AGGCTACGAACTGAAGCTCAGCTACATCCCCGGCACGATGCCGCGCCAATATTTTGATAACGACACTTCCGCTCTCAAAG
ACTCCACCCTCGCCCAAGAGCTGCGCACCTTTGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTT
GTCTTGCGCCGCATTACAGATGACCAGGACAGGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTTGGCGGCAGAGG
CGCATACGCCTTGGATTTGACCAAAATCGACAACAGCAACCTGACCGGCGTTTCCATGTTTGATGTCAAAAACGAGAGTA
AAAATAATGGCGTGAAATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAATCCGCAACGGCAAATACGCCGCCTTC
CTCGCCTCCGGTTATGCGGCTAAAGATATTGTCAGCAGCGATAATACAACCGCGCTGTATGTGTATGATTTGGGAAACGG
CGGTGGTAGTCTGATTAAAAAAATCGAAGCACCCGGCGGCAAAGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATT
TGGACGGCATTGTCGATATCGCCTATGCCGGCGACCGGGGCGGCAATATGTACCGCTTTGATTTGAGCGGCGACAATCCG
TCCAAATGGACTGTACGCACTATTTTCCAAGGCACAAAACCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAA
ACGCGTGGTCATCTTCGGTACGGGCAGCGATTTGAGTGAACAGGATGTAGTCGATAAGGATCAACAATATATTTACGGTA
TCTTTGACGACGATAAGGGGACGGTTAAGGTAACGGTACAAAACGGCACGGGAGGCGGGCTGCTCGAGCAAGTGCTTAAA
GAGGAAAATAAAACATTATTCCTGAACAAGGGATCCGACGGATCGGGCAGTAAGGGGTGGGTAGTGAAGCTGAAGGAAGG
ACAGCGCGTTACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTCGTAACCATCCGCAAGTATAAAGACGACGGCTGCG
GCGCGGATACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCG
GAAGCCAATAAGGATGTCGCACAATATTCCGGCCATAAGACAACCTCCAAAGGCAAATCCATCCCTATAGGTTGTATGGA
AAAAGGCGGTAAAACCGTCTGCCCGAACGGATATGTTTACGACAAGCCGGTTAATGTGCGTTATCTGGACGAAAAGAAAA
CAGACGATTTCCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAAT
AACCGGTGCTTCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTG
CGGTATCAAACGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(472-808)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

71.372

100

0.724