Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   OCL42_RS09425 Genome accession   NZ_CP106807
Coordinates   1797649..1798902 (-) Length   417 a.a.
NCBI ID   WP_003687004.1    Uniprot ID   A0AB74EGQ8
Organism   Neisseria gonorrhoeae strain 10736     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1792649..1803902
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  OCL42_RS09395 (OCL42_09395) lpxC 1793270..1794193 (+) 924 WP_003687007.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -
  OCL42_RS09400 (OCL42_09400) - 1794321..1794716 (+) 396 Protein_1820 pilin -
  OCL42_RS09405 (OCL42_09405) - 1794834..1794908 (+) 75 Protein_1821 pilin -
  OCL42_RS09410 (OCL42_09410) pilE 1795530..1796027 (+) 498 WP_263057282.1 pilin Machinery gene
  OCL42_RS12120 - 1796681..1796890 (+) 210 WP_407028660.1 hypothetical protein -
  OCL42_RS09415 (OCL42_09415) - 1796814..1797380 (+) 567 WP_407028657.1 opacity family porin -
  OCL42_RS09420 (OCL42_09420) - 1797394..1797564 (+) 171 WP_263074894.1 hypothetical protein -
  OCL42_RS09425 (OCL42_09425) pilA 1797649..1798902 (-) 1254 WP_003687004.1 signal recognition particle-docking protein FtsY Machinery gene
  OCL42_RS09430 (OCL42_09430) msrAB 1799048..1800616 (+) 1569 WP_003696503.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  OCL42_RS09435 (OCL42_09435) - 1800700..1801182 (-) 483 WP_003694396.1 CinA family protein -
  OCL42_RS09440 (OCL42_09440) - 1801209..1802057 (-) 849 WP_003687000.1 mechanosensitive ion channel family protein -
  OCL42_RS09445 (OCL42_09445) - 1802151..1803152 (-) 1002 WP_003686999.1 thiamine ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44389.74 Da        Isoelectric Point: 4.8123

>NTDB_id=735494 OCL42_RS09425 WP_003687004.1 1797649..1798902(-) (pilA) [Neisseria gonorrhoeae strain 10736]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGGRNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=735494 OCL42_RS09425 WP_003687004.1 1797649..1798902(-) (pilA) [Neisseria gonorrhoeae strain 10736]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGGGCTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCGGGCGATACTTTCCGCGCCGCCGCGCGCGAGCAGCTTCAGGCTTG
GGGCGGGCGCAACAATGTAACCGTGATTTCACAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATGCCGTCCAAGCCG
CGAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATTATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, GTPase domain (SRP54)

(217-416)

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

99.76

100

0.998