Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   P5649_RS09025 Genome accession   NZ_CP120613
Coordinates   1761243..1761878 (+) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis strain DSM 23521     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1756243..1766878
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5649_RS09000 (P5649_09000) liaI 1757370..1757750 (+) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -
  P5649_RS09005 (P5649_09005) liaH 1757777..1758454 (+) 678 WP_003243047.1 stress responsive protein LiaH -
  P5649_RS09010 (P5649_09010) liaG 1758555..1759427 (+) 873 WP_003244420.1 DUF4097 domain-containing protein -
  P5649_RS09015 (P5649_09015) liaF 1759461..1760186 (+) 726 WP_003242605.1 LiaRS two-component regulatory system accessory protein LiaF -
  P5649_RS09020 (P5649_09020) liaS 1760183..1761265 (+) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  P5649_RS09025 (P5649_09025) vraR 1761243..1761878 (+) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  P5649_RS09030 (P5649_09030) gerAC 1761886..1763007 (-) 1122 WP_009968146.1 spore germination receptor protein GerAC -
  P5649_RS09035 (P5649_09035) gerAB 1763004..1764103 (-) 1100 Protein_1747 spore germination receptor protein GerAB -
  P5649_RS09040 (P5649_09040) gerAA 1764072..1765520 (-) 1449 WP_009969097.1 spore germination receptor protein GerAA -
  P5649_RS09045 (P5649_09045) yvzF 1765638..1765823 (+) 186 WP_003244599.1 YvzF family protein -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=733115 P5649_RS09025 WP_003243201.1 1761243..1761878(+) (vraR) [Bacillus subtilis strain DSM 23521]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=733115 P5649_RS09025 WP_003243201.1 1761243..1761878(+) (vraR) [Bacillus subtilis strain DSM 23521]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408