Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   P5711_RS09755 Genome accession   NZ_CP120568
Coordinates   2025943..2026599 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 582     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2020943..2031599
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5711_RS09725 (P5711_09725) dcyD 2021823..2022809 (+) 987 WP_001128222.1 D-cysteine desulfhydrase -
  P5711_RS09730 (P5711_09730) tcyL 2022824..2023492 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  P5711_RS09735 (P5711_09735) tcyN 2023489..2024241 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  P5711_RS09740 (P5711_09740) sdiA 2024471..2025193 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  P5711_RS09745 (P5711_09745) yecF 2025260..2025484 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  P5711_RS09750 (P5711_09750) yecU 2025471..2025647 (-) 177 WP_001326718.1 protein YecU -
  P5711_RS24595 - 2025730..2025801 (-) 72 Protein_1901 transcriptional regulator -
  P5711_RS09755 (P5711_09755) letA 2025943..2026599 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  P5711_RS09760 (P5711_09760) uvrC 2026596..2028428 (+) 1833 WP_001283429.1 excinuclease ABC subunit UvrC Machinery gene
  P5711_RS09765 (P5711_09765) pgsA 2028485..2029033 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  P5711_RS09785 (P5711_09785) yecA 2029683..2030348 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=732575 P5711_RS09755 WP_000611335.1 2025943..2026599(+) (letA) [Escherichia coli strain 582]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=732575 P5711_RS09755 WP_000611335.1 2025943..2026599(+) (letA) [Escherichia coli strain 582]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486