Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   P5707_RS11130 Genome accession   NZ_CP120567
Coordinates   2353792..2354448 (+) Length   218 a.a.
NCBI ID   WP_180555196.1    Uniprot ID   -
Organism   Escherichia coli strain A0 34/86     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2348792..2359448
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5707_RS11100 (P5707_11100) dcyD 2349671..2350657 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  P5707_RS11105 (P5707_11105) tcyL 2350672..2351340 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  P5707_RS11110 (P5707_11110) tcyN 2351337..2352089 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  P5707_RS11115 (P5707_11115) sdiA 2352319..2353041 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  P5707_RS11120 (P5707_11120) yecF 2353109..2353333 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  P5707_RS11125 (P5707_11125) yecU 2353320..2353496 (-) 177 WP_001307856.1 protein YecU -
  P5707_RS11130 (P5707_11130) letA 2353792..2354448 (+) 657 WP_180555196.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  P5707_RS11135 (P5707_11135) uvrC 2354445..2356277 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  P5707_RS11140 (P5707_11140) pgsA 2356334..2356882 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  P5707_RS11160 (P5707_11160) - 2357876..2358157 (+) 282 WP_071529678.1 hypothetical protein -
  P5707_RS11165 (P5707_11165) - 2358347..2358487 (-) 141 WP_000078920.1 Hok/Gef family protein -
  P5707_RS11170 (P5707_11170) - 2358677..2358937 (-) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23905.66 Da        Isoelectric Point: 7.3522

>NTDB_id=732501 P5707_RS11130 WP_180555196.1 2353792..2354448(+) (letA) [Escherichia coli strain A0 34/86]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
RTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=732501 P5707_RS11130 WP_180555196.1 2353792..2354448(+) (letA) [Escherichia coli strain A0 34/86]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CGTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482