Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   P5709_RS06570 Genome accession   NZ_CP120557
Coordinates   1277979..1278635 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain B771     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1272979..1283635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P5709_RS06540 (P5709_06540) yecA 1274231..1274896 (-) 666 WP_000847880.1 UPF0149 family protein YecA -
  P5709_RS06560 (P5709_06560) pgsA 1275545..1276093 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  P5709_RS06565 (P5709_06565) uvrC 1276150..1277982 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  P5709_RS06570 (P5709_06570) letA 1277979..1278635 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  P5709_RS26265 - 1278777..1278893 (+) 117 WP_001302039.1 hypothetical protein -
  P5709_RS06575 (P5709_06575) yecU 1278931..1279107 (+) 177 WP_000590344.1 protein YecU -
  P5709_RS06580 (P5709_06580) yecF 1279094..1279318 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  P5709_RS06585 (P5709_06585) sdiA 1279386..1280108 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  P5709_RS06590 (P5709_06590) tcyN 1280338..1281090 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  P5709_RS06595 (P5709_06595) tcyL 1281087..1281755 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  P5709_RS06600 (P5709_06600) dcyD 1281770..1282756 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=732293 P5709_RS06570 WP_000611328.1 1277979..1278635(-) (letA) [Escherichia coli strain B771]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=732293 P5709_RS06570 WP_000611328.1 1277979..1278635(-) (letA) [Escherichia coli strain B771]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482