Detailed information NTG0730465

Bioinformatically predicted

Overview

• Name: luxQ
• Type: Regulator
• Locus tag: N5E84_RS18385
• Genome accession: NZ_CP104555
• Coordinates: 605367..607913 (+)
• Length: 848 a.a.
• NCBI ID: WP_069212121.1
• Uniprot ID: A0A289GHL7
• Organism: Vibrio sp. J502
• Function: autoinducer sensor (predicted from homology) Competence regulation

Genomic Context

Location: 600367..612913

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
N5E84_RS18350 (N5E84_18350)	-	600471..600722 (-)	252	WP_010319896.1	YgjV family protein	-
N5E84_RS18355 (N5E84_18355)	-	601030..601347 (-)	318	WP_010319897.1	DUF496 family protein	-
N5E84_RS18360 (N5E84_18360)	-	601538..601741 (+)	204	WP_026027876.1	hypothetical protein	-
N5E84_RS18365 (N5E84_18365)	-	601799..602452 (+)	654	WP_019282227.1	YceH family protein	-
N5E84_RS18370 (N5E84_18370)	-	602453..602776 (+)	324	WP_013867913.1	GIY-YIG nuclease family protein	-
N5E84_RS18375 (N5E84_18375)	-	602872..604023 (+)	1152	WP_019282226.1	conjugal transfer protein TraF	-
N5E84_RS18380 (N5E84_18380)	luxP	604248..605351 (+)	1104	WP_069212120.1	autoinducer 2-binding periplasmic protein LuxP	Regulator
N5E84_RS18385 (N5E84_18385)	luxQ	605367..607913 (+)	2547	WP_069212121.1	quorum-sensing autoinducer 2 sensor kinase/phosphatase LuxQ	Regulator
N5E84_RS18390 (N5E84_18390)	-	607931..608596 (-)	666	WP_019282225.1	flagellar brake protein	-
N5E84_RS18395 (N5E84_18395)	glpD	608740..610284 (-)	1545	WP_019282224.1	glycerol-3-phosphate dehydrogenase	-
N5E84_RS18400 (N5E84_18400)	-	610471..611730 (-)	1260	WP_069212122.1	hydroxymethylglutaryl-CoA reductase	-
N5E84_RS18405 (N5E84_18405)	-	611818..612117 (-)	300	WP_017047233.1	hypothetical protein	-
N5E84_RS18410 (N5E84_18410)	-	612185..612409 (-)	225	WP_013867905.1	hypothetical protein	-

Sequence

Protein

• Length: 848 a.a.
• Molecular weight: 96093.71 Da
• Isoelectric Point: 5.0898

>NTDB_id=730465 N5E84_RS18385 WP_069212121.1 605367..607913(+) (luxQ) [Vibrio sp. J502]
MSLRSSTVKKKQKIATVITKSMIAVIGALTLSVLFQSYQISSKIIAQEVQRTASQTSSLIQNLFNFRLSLLQINQDSSAK
NAGLVKAIRKGDNDSIDQFFFGVDQLEVANTPDIRFISDSDSLMWEDGNAQFYGIEQNELVNMSRKVALSNNWHMSKSPS
QLGYAYLMVRRTPVIDSQSGEVIGFLHLATVLNNNYVLAETLREGSNSENLVMTTGEKVLASTINGDETYTERDVLEDNF
DAYSFADYMVSRTALTIEGVPIYINVLSVQSNENVLQLRENYFFWMIFALFAMVIVSILTRWWLQQRVKNEISSLMNYTH
KAAEAGSYELFSGSKIYEFDHFGRTLEHTFQRLSEQEKQFEDLFNFSLSPIIVWSIDGDIIKMNPSAKKYFMRRNDQQQC
ILDALKQELQPKIRLAVEQETFREINVEVGNKVFRWNLSPIIFEQRIESIITQGQDITTIAEAAKQSRLARQEAEESARI
RAEFLAKMSHELRTPLNGILGVSQLLKREISDHEQLEQVNVLCSSGEHLLAVLNDILDFSKIEQGQFRIQESDFKLVEVI
SAVESIYRPLCAEKEIEFSLKSNIPPDMMIHSDQVRLNQILFNLLNNATKFTHNGLISIEFQQKNNHQLFISISDTGIGI
REQDLALIFEPFTQVESNTTREYGGSGLGLAIVKSLIEMLGGAVNVKSQFGVGTTFSVELPLVVVSDCGKDIPSYERAPP
HEMFEKPIKVLLVEDNHTNAFIAQAFCKKYGMEVTRVEDGLQAIDYVKDHPVDLILMDNQLPYLGGVETTHLIKHEMMMD
VPIYACTADGMQSTNEAFMAAGAEYVIVKPIKEKALHEAFCHFQKRQK

Nucleotide

• Length: 2547 bp

>NTDB_id=730465 N5E84_RS18385 WP_069212121.1 605367..607913(+) (luxQ) [Vibrio sp. J502]
ATGAGTTTAAGGTCAAGCACCGTCAAGAAAAAACAAAAGATAGCTACCGTGATCACCAAATCAATGATTGCGGTGATTGG
CGCATTGACGCTCAGCGTTTTATTTCAAAGTTATCAGATCAGTAGCAAAATCATTGCTCAAGAAGTGCAACGTACGGCTT
CTCAAACCTCTAGTCTCATCCAGAACCTCTTTAACTTCCGTCTTTCATTACTGCAGATAAACCAAGATAGCAGCGCAAAA
AATGCAGGTTTAGTTAAAGCAATTCGTAAGGGCGATAATGACAGCATTGATCAGTTCTTTTTTGGAGTTGACCAGCTAGA
AGTAGCCAACACGCCTGACATTCGTTTCATTTCTGATTCTGACAGCCTGATGTGGGAAGATGGCAATGCTCAGTTTTATG
GTATTGAACAAAACGAGCTGGTAAACATGTCTCGTAAAGTCGCGTTAAGTAATAACTGGCATATGAGCAAATCGCCCTCT
CAATTGGGCTATGCCTACCTAATGGTCAGACGTACTCCCGTTATTGACTCGCAGTCCGGAGAGGTGATTGGTTTTTTGCA
TCTTGCTACCGTACTTAACAACAATTACGTGCTGGCAGAAACATTACGTGAAGGGAGTAACTCAGAAAATCTCGTGATGA
CGACGGGTGAAAAGGTCTTAGCCTCAACAATTAATGGTGATGAGACCTACACGGAACGTGATGTTTTAGAAGATAATTTT
GACGCCTATAGTTTTGCCGATTACATGGTAAGCCGTACCGCGTTAACCATAGAAGGCGTACCAATTTATATTAACGTCCT
CAGTGTGCAGAGCAATGAGAACGTATTGCAATTACGTGAAAATTATTTTTTTTGGATGATTTTTGCCCTTTTTGCGATGG
TGATAGTCTCTATTTTGACTCGTTGGTGGTTACAGCAGCGTGTCAAAAATGAAATCAGTAGCTTGATGAATTACACCCAC
AAAGCTGCAGAAGCTGGGAGTTATGAGCTTTTTTCTGGTTCTAAAATCTATGAATTTGATCACTTCGGCAGAACGCTAGA
ACACACATTTCAACGTTTATCTGAGCAAGAAAAACAATTTGAAGATCTGTTCAATTTTTCACTTTCGCCCATCATAGTAT
GGAGTATCGACGGTGATATCATCAAAATGAACCCATCAGCAAAGAAATATTTCATGCGTCGCAATGATCAACAGCAATGC
ATTCTTGATGCATTAAAGCAAGAACTGCAGCCAAAGATACGCCTTGCGGTTGAACAAGAAACGTTCCGAGAGATAAACGT
TGAAGTTGGCAACAAGGTTTTTCGCTGGAATTTATCGCCCATTATTTTTGAGCAGAGAATTGAGTCAATCATCACTCAAG
GACAAGATATTACGACAATCGCTGAGGCGGCCAAACAGAGCCGACTCGCAAGACAAGAAGCGGAAGAGTCGGCGCGTATT
CGTGCTGAATTTCTTGCAAAAATGAGCCATGAGCTGAGAACACCATTGAATGGAATTTTAGGGGTTTCTCAATTACTTAA
GCGTGAAATCAGTGACCATGAGCAACTTGAACAAGTGAATGTGTTATGCAGTAGTGGTGAACATTTATTGGCGGTGCTGA
ATGATATCCTTGATTTTTCAAAGATAGAGCAGGGACAGTTTAGAATTCAAGAGTCTGACTTTAAGCTGGTTGAGGTCATC
TCTGCCGTGGAAAGTATCTATCGGCCATTATGTGCGGAAAAAGAGATTGAGTTCAGCCTAAAGAGCAATATTCCGCCTGA
TATGATGATCCATAGCGATCAAGTCCGCCTGAACCAAATTCTGTTTAATTTATTAAATAATGCGACTAAGTTTACCCATA
ATGGGTTGATTAGCATTGAGTTCCAGCAAAAGAATAACCACCAATTGTTTATTTCGATTAGTGATACAGGTATCGGCATC
AGAGAGCAAGATCTCGCGCTTATTTTTGAGCCTTTTACTCAAGTAGAATCAAACACCACACGAGAATACGGCGGTAGTGG
TTTGGGGCTTGCGATTGTCAAAAGCTTAATTGAGATGCTTGGTGGTGCCGTAAACGTGAAAAGCCAATTTGGAGTAGGTA
CTACATTTTCTGTTGAACTCCCGCTGGTTGTCGTGAGTGACTGCGGGAAGGATATACCATCTTATGAGCGCGCGCCGCCA
CATGAAATGTTTGAAAAACCAATCAAAGTGTTGCTAGTCGAAGATAATCATACCAACGCTTTTATTGCTCAAGCATTTTG
CAAAAAATACGGTATGGAAGTGACAAGAGTAGAGGATGGTCTACAGGCGATTGATTATGTGAAAGATCATCCAGTGGATC
TTATCTTAATGGATAACCAACTGCCTTACTTAGGAGGGGTTGAAACAACCCATTTAATCAAACACGAGATGATGATGGAT
GTACCCATTTATGCGTGTACAGCTGATGGCATGCAATCGACTAACGAAGCATTTATGGCCGCAGGTGCAGAGTATGTGAT
AGTTAAACCTATCAAAGAGAAAGCATTGCATGAGGCTTTTTGTCACTTCCAAAAACGGCAGAAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (593-702)

• LuxQ, periplasmic (LuxQ-periplasm) (41-278)

• His Kinase A (phospho-acceptor) domain (HisKA) (481-545)

• Response regulator receiver domain (Response_reg) (730-839)

3D structure

• AlphaFold DB: A0A289GHL7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
luxQ	Vibrio cholerae strain A1552	56.537	100	0.566