Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   GDK18_RS14760 Genome accession   NZ_AP019543
Coordinates   2862316..2862981 (-) Length   221 a.a.
NCBI ID   WP_152064787.1    Uniprot ID   -
Organism   Staphylococcus aureus strain KG-18     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2857316..2867981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GDK18_RS14740 - 2857786..2857899 (-) 114 Protein_2813 hypothetical protein -
  GDK18_RS14745 (SAKG18_27040) - 2858558..2860558 (-) 2001 WP_000776751.1 ABC transporter permease -
  GDK18_RS14750 (SAKG18_27050) - 2860555..2861310 (-) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  GDK18_RS14755 (SAKG18_27060) braS 2861418..2862305 (-) 888 WP_000143425.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  GDK18_RS14760 (SAKG18_27070) braR 2862316..2862981 (-) 666 WP_152064787.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  GDK18_RS14765 (SAKG18_27080) - 2863007..2863207 (-) 201 WP_000604730.1 hypothetical protein -
  GDK18_RS14770 (SAKG18_27090) - 2863405..2864829 (+) 1425 WP_000953755.1 alkaline phosphatase -
  GDK18_RS15385 - 2864899..2865009 (+) 111 Protein_2820 hypothetical protein -
  GDK18_RS14780 (SAKG18_27110) - 2865112..2865567 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  GDK18_RS14785 (SAKG18_27120) - 2865812..2866573 (-) 762 WP_000323441.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25357.45 Da        Isoelectric Point: 4.9212

>NTDB_id=72794 GDK18_RS14760 WP_152064787.1 2862316..2862981(-) (braR) [Staphylococcus aureus strain KG-18]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGGDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=72794 GDK18_RS14760 WP_152064787.1 2862316..2862981(-) (braR) [Staphylococcus aureus strain KG-18]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGGTGATTTTATCGAAAAGCCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment