Detailed information NTG0072793

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: GDK18_RS14755
• Genome accession: NZ_AP019543
• Coordinates: 2861418..2862305 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain KG-18
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2856418..2867305

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GDK18_RS14720	-	2856437..2856529 (+)	93	WP_010956583.1	hypothetical protein	-
GDK18_RS14725 (SAKG18_27020)	-	2856637..2857134 (-)	498	WP_001065268.1	glutathione peroxidase	-
GDK18_RS14730 (SAKG18_27030)	-	2857144..2857404 (-)	261	WP_001791974.1	hypothetical protein	-
GDK18_RS14740	-	2857786..2857899 (-)	114	Protein_2813	hypothetical protein	-
GDK18_RS14745 (SAKG18_27040)	-	2858558..2860558 (-)	2001	WP_000776751.1	ABC transporter permease	-
GDK18_RS14750 (SAKG18_27050)	-	2860555..2861310 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
GDK18_RS14755 (SAKG18_27060)	braS	2861418..2862305 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
GDK18_RS14760 (SAKG18_27070)	braR	2862316..2862981 (-)	666	WP_152064787.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
GDK18_RS14765 (SAKG18_27080)	-	2863007..2863207 (-)	201	WP_000604730.1	hypothetical protein	-
GDK18_RS14770 (SAKG18_27090)	-	2863405..2864829 (+)	1425	WP_000953755.1	alkaline phosphatase	-
GDK18_RS15385	-	2864899..2865009 (+)	111	Protein_2820	hypothetical protein	-
GDK18_RS14780 (SAKG18_27110)	-	2865112..2865567 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
GDK18_RS14785 (SAKG18_27120)	-	2865812..2866573 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=72793 GDK18_RS14755 WP_000143425.1 2861418..2862305(-) (braS) [Staphylococcus aureus strain KG-18]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=72793 GDK18_RS14755 WP_000143425.1 2861418..2862305(-) (braS) [Staphylococcus aureus strain KG-18]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1