Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   P3M65_RS05340 Genome accession   NZ_CP119719
Coordinates   1070481..1071137 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain IZSBS22     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1065481..1076137
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P3M65_RS05310 yecA 1066732..1067397 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  P3M65_RS05330 pgsA 1068047..1068595 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  P3M65_RS05335 uvrC 1068652..1070484 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  P3M65_RS05340 letA 1070481..1071137 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  P3M65_RS05345 - 1071279..1071350 (+) 72 Protein_1056 transcriptional regulator -
  P3M65_RS05350 yecU 1071433..1071609 (+) 177 WP_000590347.1 protein YecU -
  P3M65_RS05355 yecF 1071596..1071820 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  P3M65_RS05360 sdiA 1071887..1072609 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  P3M65_RS05365 tcyN 1072839..1073591 (-) 753 WP_001272986.1 L-cystine ABC transporter ATP-binding protein TcyN -
  P3M65_RS05370 tcyL 1073588..1074256 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  P3M65_RS05375 dcyD 1074271..1075257 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=727671 P3M65_RS05340 WP_000611335.1 1070481..1071137(-) (letA) [Escherichia coli strain IZSBS22]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=727671 P3M65_RS05340 WP_000611335.1 1070481..1071137(-) (letA) [Escherichia coli strain IZSBS22]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486