Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   N2A94_RS06485 Genome accession   NZ_CP104048
Coordinates   1276012..1277316 (-) Length   434 a.a.
NCBI ID   WP_045407612.1    Uniprot ID   A0A0E2UDU5
Organism   Streptococcus parauberis strain KSP20     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1271012..1282316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N2A94_RS06475 (N2A94_06475) hpf 1274728..1275276 (-) 549 WP_003105371.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  N2A94_RS06480 (N2A94_06480) - 1275351..1275953 (-) 603 WP_238570166.1 ComF family protein -
  N2A94_RS06485 (N2A94_06485) comFA/cflA 1276012..1277316 (-) 1305 WP_045407612.1 DEAD/DEAH box helicase Machinery gene
  N2A94_RS06490 (N2A94_06490) - 1277373..1278005 (+) 633 WP_003107489.1 YigZ family protein -
  N2A94_RS06495 (N2A94_06495) cysK 1278128..1279057 (+) 930 WP_003103108.1 cysteine synthase A -
  N2A94_RS06500 (N2A94_06500) - 1279133..1279486 (-) 354 WP_003103672.1 S1 RNA-binding domain-containing protein -
  N2A94_RS06505 (N2A94_06505) - 1279486..1280886 (-) 1401 WP_045407608.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  N2A94_RS06510 (N2A94_06510) - 1280920..1281561 (-) 642 WP_003107492.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 434 a.a.        Molecular weight: 49703.69 Da        Isoelectric Point: 9.6231

>NTDB_id=727354 N2A94_RS06485 WP_045407612.1 1276012..1277316(-) (comFA/cflA) [Streptococcus parauberis strain KSP20]
MGKNYYEQGRLFTEQQMKNVITAKTFSMKESMSMESGKQCCNRCFQEVAKTNLLPNGKTYCRFCIAFGRVESESQLYYFA
PQAFPKGDYLRWNGQLTPYQEKISEFLLGNYLNKKNSLVHAVTGAGKTEMIYKLIESVINQGGWVCFTSPRVDVCIDIKN
RLVRDFSCPITIMYGGSEEYRPAPLIVSTTHQLLKFYRAFDLLIIDEVDAFPFLGNVVLNKATQSCLKEEGKVVCLTATS
TNELEQKVSDGHYEKIRLSRRFHNHPLVVPKFQLIYPLSKQFEKNKFPNLLSNLISQQRQTAFPLLIFYPLITEGEKFTK
ILQKAFPKEKIAFVSSKSDDRKEKIDAFKKRQIDILVTTTILERGVTFPEVDVYVILANHKLFTSSSLIQIAGRVGRSVS
RPSGQLLFIHEGVSLQMKKARKQIIEMNKEAYGE

Nucleotide


Download         Length: 1305 bp        

>NTDB_id=727354 N2A94_RS06485 WP_045407612.1 1276012..1277316(-) (comFA/cflA) [Streptococcus parauberis strain KSP20]
ATGGGAAAAAATTATTATGAACAAGGTCGACTTTTTACTGAACAACAAATGAAAAATGTGATAACTGCGAAAACTTTTTC
CATGAAAGAAAGTATGAGTATGGAGTCTGGTAAGCAATGTTGCAATAGATGTTTTCAAGAAGTTGCTAAAACTAATCTTT
TACCTAATGGGAAGACATATTGTAGATTTTGTATTGCCTTTGGTCGGGTGGAATCTGAATCACAACTCTATTATTTTGCA
CCTCAAGCATTTCCGAAAGGTGATTATTTACGCTGGAATGGTCAACTAACCCCATATCAAGAAAAAATTTCAGAATTTTT
GTTAGGCAATTATCTTAATAAAAAAAACAGCTTAGTCCATGCTGTGACAGGTGCTGGAAAAACAGAAATGATATATAAAT
TAATTGAATCAGTAATCAATCAAGGTGGCTGGGTCTGTTTTACTAGTCCCCGAGTAGATGTCTGTATTGATATCAAAAAT
CGTTTAGTTCGAGACTTCTCTTGCCCAATAACAATTATGTATGGAGGGTCCGAGGAATATCGTCCAGCTCCCTTGATAGT
TTCAACAACACATCAACTCTTAAAATTTTATCGAGCCTTTGATTTATTAATAATAGATGAAGTTGATGCTTTTCCTTTTT
TAGGGAATGTGGTTCTAAATAAAGCAACACAATCATGTTTAAAAGAGGAAGGTAAAGTTGTTTGTCTGACTGCGACTTCG
ACAAATGAATTAGAACAAAAAGTCAGCGATGGACATTATGAAAAAATAAGATTGTCAAGACGTTTCCATAATCATCCATT
GGTCGTTCCTAAGTTTCAATTAATTTATCCATTATCAAAACAGTTTGAAAAAAATAAATTTCCTAACTTACTAAGTAATT
TGATTAGTCAACAAAGACAGACTGCATTCCCTTTACTAATTTTCTACCCTCTAATTACAGAAGGGGAAAAATTTACGAAA
ATATTGCAAAAAGCTTTTCCTAAAGAAAAAATTGCCTTTGTATCAAGTAAATCTGATGATCGAAAAGAGAAAATTGATGC
GTTTAAAAAAAGACAAATTGATATTCTTGTAACTACGACTATTTTGGAGAGGGGAGTAACATTTCCAGAAGTAGATGTTT
ACGTTATTTTGGCAAATCATAAGCTATTTACGAGTAGTAGCCTGATTCAGATAGCAGGTCGCGTAGGGAGATCCGTATCT
CGACCAAGTGGGCAGTTACTATTTATTCATGAAGGGGTAAGTCTACAAATGAAGAAAGCTCGTAAACAAATTATAGAAAT
GAATAAGGAAGCATATGGTGAATAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(95-207)

Helicase conserved C-terminal domain (Helicase_C)

(289-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2UDU5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae D39

53.052

98.157

0.521
  comFA/cflA Streptococcus pneumoniae R6

53.052

98.157

0.521
  comFA/cflA Streptococcus pneumoniae TIGR4

53.052

98.157

0.521
  comFA/cflA Streptococcus pneumoniae Rx1

53.052

98.157

0.521
  comFA/cflA Streptococcus mitis SK321

52.347

98.157

0.514
  comFA/cflA Streptococcus mitis NCTC 12261

51.643

98.157

0.507
  comFA Lactococcus lactis subsp. cremoris KW2

48.744

91.705

0.447
  comFA Latilactobacillus sakei subsp. sakei 23K

35.202

100

0.362