Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   P1J04_RS09355 Genome accession   NZ_CP119577
Coordinates   1940803..1941459 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain C012_chr     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1935803..1946459
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  P1J04_RS09320 (P1J04_09315) dcyD 1936683..1937669 (+) 987 WP_001128242.1 D-cysteine desulfhydrase -
  P1J04_RS09325 (P1J04_09320) tcyL 1937684..1938352 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  P1J04_RS09330 (P1J04_09325) tcyN 1938349..1939101 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  P1J04_RS09335 (P1J04_09330) sdiA 1939331..1940053 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  P1J04_RS09340 (P1J04_09335) yecF 1940120..1940344 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  P1J04_RS09345 (P1J04_09340) yecU 1940331..1940507 (-) 177 WP_000590347.1 protein YecU -
  P1J04_RS09350 (P1J04_26670) - 1940590..1940661 (-) 72 Protein_1831 transcriptional regulator -
  P1J04_RS09355 (P1J04_09345) letA 1940803..1941459 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  P1J04_RS09360 (P1J04_09350) uvrC 1941456..1943288 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  P1J04_RS09365 (P1J04_09355) pgsA 1943345..1943893 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  P1J04_RS09385 (P1J04_09375) yecA 1944543..1945208 (+) 666 WP_112039825.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=726746 P1J04_RS09355 WP_000611335.1 1940803..1941459(+) (letA) [Escherichia coli strain C012_chr]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=726746 P1J04_RS09355 WP_000611335.1 1940803..1941459(+) (letA) [Escherichia coli strain C012_chr]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486