Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PWR57_RS13605 Genome accession   NZ_CP119441
Coordinates   2696231..2696887 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli O121 strain 201805972     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2691231..2701887
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWR57_RS13575 (PWR57_13555) yecA 2692482..2693147 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  PWR57_RS13595 (PWR57_13575) pgsA 2693797..2694345 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PWR57_RS13600 (PWR57_13580) uvrC 2694402..2696234 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PWR57_RS13605 (PWR57_13585) letA 2696231..2696887 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PWR57_RS13610 - 2697029..2697100 (+) 72 Protein_2658 transcriptional regulator -
  PWR57_RS13615 (PWR57_13590) yecU 2697183..2697359 (+) 177 WP_001307856.1 protein YecU -
  PWR57_RS13620 (PWR57_13595) yecF 2697346..2697570 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PWR57_RS13625 (PWR57_13600) sdiA 2697637..2698359 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  PWR57_RS13630 (PWR57_13605) tcyN 2698589..2699341 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PWR57_RS13635 (PWR57_13610) tcyL 2699338..2700006 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PWR57_RS13640 (PWR57_13615) dcyD 2700021..2701007 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=726466 PWR57_RS13605 WP_000611335.1 2696231..2696887(-) (letA) [Escherichia coli O121 strain 201805972]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=726466 PWR57_RS13605 WP_000611335.1 2696231..2696887(-) (letA) [Escherichia coli O121 strain 201805972]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486