Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PX810_RS09255 Genome accession   NZ_CP119402
Coordinates   1920405..1921061 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MRE162 substr. FRA     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1915405..1926061
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PX810_RS09225 (PX810_001845) dcyD 1916284..1917270 (+) 987 WP_275772361.1 D-cysteine desulfhydrase -
  PX810_RS09230 (PX810_001846) tcyL 1917285..1917953 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PX810_RS09235 (PX810_001847) tcyN 1917950..1918702 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PX810_RS09240 (PX810_001848) sdiA 1918932..1919654 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  PX810_RS09245 (PX810_001849) yecF 1919722..1919946 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PX810_RS09250 (PX810_001850) yecU 1919933..1920109 (-) 177 WP_000590347.1 protein YecU -
  PX810_RS23230 - 1920192..1920263 (-) 72 Protein_1807 transcriptional regulator -
  PX810_RS09255 (PX810_001851) letA 1920405..1921061 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PX810_RS09260 (PX810_001852) uvrC 1921058..1922890 (+) 1833 WP_275772366.1 excinuclease ABC subunit UvrC Machinery gene
  PX810_RS09265 (PX810_001853) pgsA 1922947..1923495 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PX810_RS09285 (PX810_001857) yecA 1924144..1924809 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=726207 PX810_RS09255 WP_000611335.1 1920405..1921061(+) (letA) [Escherichia coli strain MRE162 substr. FRA]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=726207 PX810_RS09255 WP_000611335.1 1920405..1921061(+) (letA) [Escherichia coli strain MRE162 substr. FRA]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486