Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PX809_RS09275 Genome accession   NZ_CP119400
Coordinates   1925494..1926150 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MRE162 substr. NOR     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1920494..1931150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PX809_RS09245 (PX809_001849) dcyD 1921373..1922359 (+) 987 WP_275772361.1 D-cysteine desulfhydrase -
  PX809_RS09250 (PX809_001850) tcyL 1922374..1923042 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PX809_RS09255 (PX809_001851) tcyN 1923039..1923791 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PX809_RS09260 (PX809_001852) sdiA 1924021..1924743 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  PX809_RS09265 (PX809_001853) yecF 1924811..1925035 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PX809_RS09270 (PX809_001854) yecU 1925022..1925198 (-) 177 WP_000590347.1 protein YecU -
  PX809_RS23235 - 1925281..1925352 (-) 72 Protein_1811 transcriptional regulator -
  PX809_RS09275 (PX809_001855) letA 1925494..1926150 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PX809_RS09280 (PX809_001856) uvrC 1926147..1927979 (+) 1833 WP_275772366.1 excinuclease ABC subunit UvrC Machinery gene
  PX809_RS09285 (PX809_001857) pgsA 1928036..1928584 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PX809_RS09305 (PX809_001861) yecA 1929233..1929898 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=726126 PX809_RS09275 WP_000611335.1 1925494..1926150(+) (letA) [Escherichia coli strain MRE162 substr. NOR]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=726126 PX809_RS09275 WP_000611335.1 1925494..1926150(+) (letA) [Escherichia coli strain MRE162 substr. NOR]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486