Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   PY824_RS02560 Genome accession   NZ_CP119172
Coordinates   458009..458653 (+) Length   214 a.a.
NCBI ID   WP_009853571.1    Uniprot ID   A0A060RG88
Organism   Streptococcus macedonicus strain SGM CIP105683     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 453009..463653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY824_RS02540 (PY824_02540) - 453544..454281 (+) 738 WP_014294069.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  PY824_RS02545 (PY824_02545) pknB 454281..456197 (+) 1917 WP_014294070.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  PY824_RS02550 (PY824_02550) liaF 456308..457003 (+) 696 WP_014294071.1 cell wall-active antibiotics response protein LiaF -
  PY824_RS02555 (PY824_02555) - 457000..458025 (+) 1026 WP_014294072.1 sensor histidine kinase -
  PY824_RS02560 (PY824_02560) vraR 458009..458653 (+) 645 WP_009853571.1 response regulator transcription factor Regulator
  PY824_RS02565 (PY824_02565) - 458772..460172 (+) 1401 WP_115265993.1 Cof-type HAD-IIB family hydrolase -
  PY824_RS02570 (PY824_02570) - 460172..460528 (+) 357 WP_014294074.1 S1 RNA-binding domain-containing protein -
  PY824_RS02575 (PY824_02575) cysK 460648..461577 (-) 930 WP_014294075.1 cysteine synthase A -
  PY824_RS02580 (PY824_02580) - 461681..462373 (-) 693 WP_115265994.1 YigZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23939.71 Da        Isoelectric Point: 4.6633

>NTDB_id=725397 PY824_RS02560 WP_009853571.1 458009..458653(+) (vraR) [Streptococcus macedonicus strain SGM CIP105683]
MTQKIKVILVDDHEMVRLGLKSFLNLQPDVEVVGEAGNGLDGINLALELKPDVVVMDLVMPEMSGVEATLKLLEEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDMQPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=725397 PY824_RS02560 WP_009853571.1 458009..458653(+) (vraR) [Streptococcus macedonicus strain SGM CIP105683]
ATGACCCAGAAAATTAAAGTTATCCTAGTTGATGACCATGAAATGGTACGTTTAGGGTTAAAAAGTTTTTTGAATTTGCA
ACCAGATGTTGAGGTGGTTGGCGAAGCTGGAAATGGTTTAGATGGTATCAATTTGGCTTTAGAATTAAAACCAGATGTGG
TTGTTATGGATTTGGTAATGCCAGAAATGAGCGGTGTCGAAGCAACATTGAAGCTTCTGGAAGAATGGAAGGAAGCTAAA
ATTCTTGTTTTAACATCTTACCTTGATAACGAAAAAATTTATCCTGTCATTGAAGCAGGGGCCAAAGGTTATATGTTAAA
AACATCTAGCGCAGCAGAAATTTTAAATGCCATTCAGAAAGTTGCACGTGGTGAGTTAGCTATTGAAACAGAAGTCGATA
AAAAAATCAAAGCCCATGATATGCAACCAGAATTGCATGAAGATTTGACAGCGCGTGAACGTGATATTTTGAGATTACTT
GCTAAAGGGTATGATAATCAAACTATTGCTGATGAGCTATTTATCTCACTAAAAACCGTCAAAACACACGTTTCAAATAT
TCTAGCTAAGTTAGAAGTTGATGACCGTACACAAGCAGTCGTTTATGCCTTTAAACATCATTTAGTACCGCAAGATGACG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A060RG88

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.427

96.262

0.505
  degU Bacillus subtilis subsp. subtilis str. 168

37.5

100

0.393