Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   PZB77_RS25245 Genome accession   NZ_CP119147
Coordinates   5796838..5797482 (+) Length   214 a.a.
NCBI ID   WP_275494914.1    Uniprot ID   -
Organism   Streptomyces sp. AM 2-1-1     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5791838..5802482
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PZB77_RS25235 (PZB77_25235) - 5794383..5795168 (-) 786 WP_275494912.1 transglycosylase SLT domain-containing protein -
  PZB77_RS25240 (PZB77_25240) - 5795700..5796845 (+) 1146 WP_275494913.1 GAF domain-containing sensor histidine kinase -
  PZB77_RS25245 (PZB77_25245) vraR 5796838..5797482 (+) 645 WP_275494914.1 response regulator transcription factor Regulator
  PZB77_RS25250 (PZB77_25250) - 5797531..5798319 (-) 789 WP_275494915.1 hypothetical protein -
  PZB77_RS25255 (PZB77_25255) - 5798465..5799262 (+) 798 WP_275494916.1 ABC transporter ATP-binding protein -
  PZB77_RS25260 (PZB77_25260) - 5799349..5799771 (+) 423 WP_275494917.1 NfeD family protein -
  PZB77_RS25265 (PZB77_25265) - 5799904..5800848 (+) 945 WP_275494918.1 SPFH domain-containing protein -
  PZB77_RS25270 (PZB77_25270) - 5800995..5801762 (+) 768 WP_275494919.1 sulfite exporter TauE/SafE family protein -
  PZB77_RS25275 (PZB77_25275) - 5801859..5802365 (-) 507 WP_275494920.1 HNH endonuclease -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23014.33 Da        Isoelectric Point: 5.6735

>NTDB_id=725296 PZB77_RS25245 WP_275494914.1 5796838..5797482(+) (vraR) [Streptomyces sp. AM 2-1-1]
MADKTIRVLLVDDHQVVRRGLRTFLEIQDDIEVVGEASDGAEGIAQAEALRPDVVLMDIKMPGTDGIEALRKLRELANPA
RVLVVTSFTEQRTVVPALRAGASGYVYKDVDPDALAGAIRSVHAGHVLLQPEVAGALLAQEDTGGGTGRGTTLTEREREV
LNLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGMAG

Nucleotide


Download         Length: 645 bp        

>NTDB_id=725296 PZB77_RS25245 WP_275494914.1 5796838..5797482(+) (vraR) [Streptomyces sp. AM 2-1-1]
GTGGCTGACAAGACCATCCGCGTGCTGCTGGTCGACGACCACCAGGTCGTACGGCGCGGGCTGCGCACCTTCCTGGAGAT
CCAGGACGACATAGAGGTCGTCGGAGAGGCGTCCGACGGAGCGGAGGGCATCGCCCAGGCCGAGGCGCTCCGCCCCGACG
TGGTGCTGATGGACATCAAGATGCCCGGCACCGACGGCATCGAGGCGCTGCGCAAGCTCCGCGAGCTGGCCAACCCGGCG
CGGGTCCTCGTCGTCACCAGCTTCACCGAGCAGCGCACGGTGGTCCCCGCCCTGCGTGCCGGAGCCTCCGGCTACGTCTA
CAAGGACGTCGACCCCGACGCACTGGCCGGCGCCATCCGCTCCGTCCACGCGGGCCACGTCCTGCTCCAGCCCGAAGTGG
CCGGCGCACTCCTCGCCCAGGAGGACACCGGCGGCGGCACCGGCCGGGGCACCACCCTCACCGAGCGCGAGCGCGAGGTG
CTCAACCTCATCGCGGACGGCCGGTCCAACCGCGAGATCGCCCGCGCGCTGGTCCTGTCCGAGAAGACCGTCAAGACCCA
CGTCTCGAACATCCTGATGAAGCTGGACCTCGCCGACCGCACCCAGGCCGCCCTGTGGGCCGTACGCCACGGCATGGCGG
GCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-119)

Bacterial regulatory proteins, luxR family (GerE)

(152-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.712

97.196

0.435
  degU Bacillus subtilis subsp. subtilis str. 168

38.462

100

0.397