Detailed information NTG0725059

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: A6P39_RS19775
• Genome accession: NZ_CP119133
• Coordinates: 4450379..4451503 (+)
• Length: 374 a.a.
• NCBI ID: WP_067052714.1
• Uniprot ID: -
• Organism: Streptomyces sp. FXJ1.172
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 4445379..4456503

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6P39_RS19760 (A6P39_019770)	-	4446046..4446906 (+)	861	WP_199840948.1	hypothetical protein	-
A6P39_RS19765 (A6P39_019775)	-	4446958..4448670 (-)	1713	WP_067052710.1	sigma-70 family RNA polymerase sigma factor	-
A6P39_RS19770 (A6P39_019780)	radA/sms	4448889..4450298 (+)	1410	WP_067052712.1	DNA repair protein RadA	Machinery gene
A6P39_RS19775 (A6P39_019785)	disA	4450379..4451503 (+)	1125	WP_067052714.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
A6P39_RS19780 (A6P39_019790)	-	4451560..4452381 (-)	822	WP_199840949.1	hypothetical protein	-
A6P39_RS19785 (A6P39_019795)	-	4452561..4453436 (+)	876	WP_067052717.1	A/G-specific adenine glycosylase	-
A6P39_RS19790 (A6P39_019800)	-	4453718..4454257 (+)	540	WP_067052719.1	SigE family RNA polymerase sigma factor	-
A6P39_RS19795 (A6P39_019805)	-	4454299..4454889 (+)	591	WP_275883988.1	hypothetical protein	-
A6P39_RS19800 (A6P39_019810)	cseB	4454978..4455682 (+)	705	WP_067051464.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 39970.67 Da
• Isoelectric Point: 4.9235

>NTDB_id=725059 A6P39_RS19775 WP_067052714.1 4450379..4451503(+) (disA) [Streptomyces sp. FXJ1.172]
MAANDRAAAPGKSGGSAGSDGLMRASLSAVAPGTALRDGLERVLRGNTGGLIVLGSDKTVEAMCTGGFVLDVEFTATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLEELIA
GVEPDRELVVRDYVPEPTAKRSRTVEEALSELDALTHAELLELGTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=725059 A6P39_RS19775 WP_067052714.1 4450379..4451503(+) (disA) [Streptomyces sp. FXJ1.172]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTTCCGATGGCCTGATGCGCGCCTCGCT
GAGCGCCGTGGCTCCCGGTACGGCCCTGCGTGACGGCCTCGAGCGCGTGCTGCGCGGCAACACCGGCGGGCTGATCGTCC
TCGGCTCGGACAAGACGGTCGAGGCGATGTGCACGGGCGGTTTCGTGCTGGACGTGGAGTTCACCGCGACCCGGCTGCGG
GAGCTGTGCAAGCTGGACGGCGGCATCGTCCTGTCGTCGGACCTGTCGAAGATCCTGCGCGCGGGCGTGCAGCTGGTGCC
GGACCCGACGATCCCGACGGAGGAGACGGGCACCCGGCACCGTACGGCGGACCGGGTGAGCAAGCAGGTCGGTTTCCCCG
TCGTCTCGGTCTCCCAGTCGATGCGCCTGATCGCCCTGTACGTGGACGGTCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTGTCCCGCGCGAACCAGGCACTGGCCACCCTGGAGCGGTACAAGCTCCGGCTGGACGAGGTGGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTCCGGGACGTCTCCGCCGTCGCCCAGCGGCTGGAGATGGTCCGGCGCATCG
CCACCGAAATCGCCGAATACGTGGTCGAACTGGGCACGGACGGCCGCCTTCTGGCCCTCCAGCTGGAGGAGCTGATCGCG
GGCGTCGAGCCGGACCGCGAGCTGGTCGTACGGGACTACGTCCCCGAGCCGACGGCGAAGCGCTCCCGCACGGTCGAGGA
GGCGCTGTCCGAGCTGGACGCGCTGACCCACGCGGAGCTGCTGGAACTCGGCACGGTGGCGCGTGCGCTCGGCTACACCG
GATCTCCTGAGACGCTGGACTCCGCGGTGTCCCCGCGGGGCTTCCGGCTGCTGGCGAAGGTTCCGCGGCTGCCGGGCGCG
ATCATCGACCGGCTGGTGGAGCATTTCGGCGGCCTGCAGAAGCTGCTCGCCGCGAGCGTCGATGACCTGCAGACCGTGGA
CGGTGTGGGCGAGGCCCGGGCGCGCAGCGTGCGGGAGGGACTGTCGCGGCTGGCGGAGTCCTCGATTCTCGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	46.532	92.513	0.43