Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PY722_RS20115 Genome accession   NZ_CP119006
Coordinates   3996656..3997312 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CE0021a     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3991656..4002312
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY722_RS20075 (PY722_20075) - 3992167..3992427 (+) 261 WP_000488112.1 ogr/Delta-like zinc finger family protein -
  PY722_RS20080 (PY722_20080) - 3992619..3992759 (+) 141 WP_000078920.1 Hok/Gef family protein -
  PY722_RS20085 (PY722_20085) - 3992948..3993229 (-) 282 WP_001303543.1 hypothetical protein -
  PY722_RS20105 (PY722_20105) pgsA 3994222..3994770 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PY722_RS20110 (PY722_20110) uvrC 3994827..3996659 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PY722_RS20115 (PY722_20115) letA 3996656..3997312 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PY722_RS27105 - 3997454..3997525 (+) 72 Protein_3940 transcriptional regulator -
  PY722_RS20120 (PY722_20120) yecU 3997608..3997784 (+) 177 WP_001326718.1 protein YecU -
  PY722_RS20125 (PY722_20125) yecF 3997771..3997995 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PY722_RS20130 (PY722_20130) sdiA 3998062..3998784 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  PY722_RS20135 (PY722_20135) tcyN 3999014..3999766 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PY722_RS20140 (PY722_20140) tcyL 3999763..4000431 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PY722_RS20145 (PY722_20145) dcyD 4000446..4001432 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=724583 PY722_RS20115 WP_000611335.1 3996656..3997312(-) (letA) [Escherichia coli strain CE0021a]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=724583 PY722_RS20115 WP_000611335.1 3996656..3997312(-) (letA) [Escherichia coli strain CE0021a]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCAGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486