Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PY719_RS12520 Genome accession   NZ_CP119003
Coordinates   2619672..2620328 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CE0026a     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2614672..2625328
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY719_RS12480 (PY719_12480) dcyD 2614774..2615760 (+) 987 WP_001565616.1 D-cysteine desulfhydrase -
  PY719_RS12485 (PY719_12485) tcyL 2615775..2616443 (+) 669 WP_001456221.1 cystine ABC transporter permease -
  PY719_RS12490 (PY719_12490) tcyN 2616440..2617192 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PY719_RS12495 (PY719_12495) sdiA 2617422..2618072 (+) 651 Protein_2430 transcriptional regulator SdiA -
  PY719_RS12505 (PY719_12505) - 2618811..2618921 (+) 111 Protein_2432 transcriptional regulator SdiA -
  PY719_RS12510 (PY719_12510) yecF 2618989..2619213 (-) 225 WP_000106473.1 DUF2594 family protein YecF -
  PY719_RS12515 (PY719_12515) yecU 2619200..2619376 (-) 177 WP_000590344.1 protein YecU -
  PY719_RS25720 - 2619414..2619530 (-) 117 WP_001302039.1 hypothetical protein -
  PY719_RS12520 (PY719_12520) letA 2619672..2620328 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PY719_RS12525 (PY719_12525) uvrC 2620325..2622157 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PY719_RS12530 (PY719_12530) pgsA 2622214..2622762 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PY719_RS12550 (PY719_12550) yecA 2623412..2624077 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=724495 PY719_RS12520 WP_000611328.1 2619672..2620328(+) (letA) [Escherichia coli strain CE0026a]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=724495 PY719_RS12520 WP_000611328.1 2619672..2620328(+) (letA) [Escherichia coli strain CE0026a]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482