Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PY720_RS24005 Genome accession   NZ_CP119000
Coordinates   5009494..5010150 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CE0026f     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 5004494..5015150
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PY720_RS23975 (PY720_23975) yecA 5005746..5006411 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  PY720_RS23995 (PY720_23995) pgsA 5007060..5007608 (-) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PY720_RS24000 (PY720_24000) uvrC 5007665..5009497 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PY720_RS24005 (PY720_24005) letA 5009494..5010150 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PY720_RS24010 (PY720_24010) yecU 5010446..5010622 (+) 177 WP_000590347.1 protein YecU -
  PY720_RS24015 (PY720_24015) yecF 5010609..5010833 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PY720_RS24020 (PY720_24020) sdiA 5010901..5011623 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  PY720_RS24025 (PY720_24025) tcyN 5011853..5012605 (-) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PY720_RS24030 (PY720_24030) tcyL 5012602..5013270 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PY720_RS24035 (PY720_24035) dcyD 5013285..5014271 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=724433 PY720_RS24005 WP_000611335.1 5009494..5010150(-) (letA) [Escherichia coli strain CE0026f]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=724433 PY720_RS24005 WP_000611335.1 5009494..5010150(-) (letA) [Escherichia coli strain CE0026f]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486