Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   PWP91_RS00355 Genome accession   NZ_CP118738
Coordinates   73100..75070 (-) Length   656 a.a.
NCBI ID   WP_058204906.1    Uniprot ID   -
Organism   Lactococcus lactis strain P-1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 68100..80070
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PWP91_RS00330 (PWP91_00330) - 68484..69668 (-) 1185 WP_014570851.1 ABC transporter permease -
  PWP91_RS00335 (PWP91_00335) - 69735..70019 (-) 285 WP_274998666.1 hypothetical protein -
  PWP91_RS00340 (PWP91_00340) - 70245..71129 (-) 885 WP_058203823.1 XRE/MutR family transcriptional regulator -
  PWP91_RS00345 (PWP91_00345) ruvB 71266..72267 (-) 1002 WP_003131994.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  PWP91_RS00350 (PWP91_00350) ruvA 72394..72987 (-) 594 WP_003131995.1 Holliday junction branch migration protein RuvA Machinery gene
  PWP91_RS00355 (PWP91_00355) hexB 73100..75070 (-) 1971 WP_058204906.1 DNA mismatch repair endonuclease MutL Machinery gene
  PWP91_RS00360 (PWP91_00360) - 75200..75895 (-) 696 WP_274998667.1 hypothetical protein -
  PWP91_RS00365 (PWP91_00365) hexA 76010..78532 (-) 2523 WP_012898701.1 DNA mismatch repair protein MutS Machinery gene
  PWP91_RS00370 (PWP91_00370) - 78726..79073 (-) 348 WP_033899277.1 RicAFT regulatory complex protein RicA family protein -

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 73774.98 Da        Isoelectric Point: 5.1824

>NTDB_id=723516 PWP91_RS00355 WP_058204906.1 73100..75070(-) (hexB) [Lactococcus lactis strain P-1]
MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKIIINVEEAGLRLIEVIDNGLGLEKEDVALALRRHATSK
IKDSADLFRIRTLGFRGEALPSIASVSQMTIETSTAEEESGTKLIAKGGNIETLEPLAKRVGTKISVANLFYNTPARLKY
IKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMRQIKGSDLDFELTGYVSIP
ELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFAILSIKIDPTLADVNVHPTKQEVRLSKERELMALISK
AIDEALSEGVLIPEALENLQGRAKEKETLSVQTELPLQNNPLYYDNVRQDFYVREEATFKINKNQPSNDSSEQTFDNFTE
NQLNTDAVNEKITDRTVESTTEITDNSLENTVSNFEIDFDNEAKISQSSTFPQLEYLAQLHATYLLCQSKEGLYLVDQHA
AQERIKYEYWKDKIGEVSMEQQILLAPYLFTLAKNDFIVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSI
NEMIDIILSSKEFSLKKYRHDLAAMVACKSSIKANHPLDAESARALLAELATCKNPYSCAHGRPTIVHFSGDDIQKMFRR
IQETHRSKAASWKDFE

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=723516 PWP91_RS00355 WP_058204906.1 73100..75070(-) (hexB) [Lactococcus lactis strain P-1]
GTGGGAAAAATTATTGAACTAAATGAAGCGCTCGCCAATCAAATTGCTGCTGGAGAGGTGGTTGAGCGGCCTGCTAGTGT
TGTCAAAGAATTAGTCGAAAACTCAATTGATGCTGGAAGCAGTAAAATTATTATCAATGTTGAAGAAGCTGGTTTGCGAT
TAATTGAAGTCATTGATAATGGTTTGGGTTTGGAAAAAGAAGATGTGGCTTTGGCTTTACGTCGTCATGCAACAAGTAAA
ATCAAGGATTCGGCAGATTTGTTTCGGATTAGAACACTTGGTTTTCGGGGGGAGGCTCTGCCATCAATCGCTTCTGTCAG
CCAGATGACCATTGAAACAAGTACGGCTGAGGAAGAATCAGGAACAAAACTAATTGCTAAAGGTGGAAATATCGAAACTT
TAGAACCGCTTGCTAAGCGCGTGGGGACGAAAATTTCTGTTGCTAATCTTTTTTATAATACACCAGCAAGACTCAAGTAT
ATCAAGTCCTTGCAGGCTGAACTTTCTCATATCACAGACATCATCAACCGATTGAGTCTGGCTCATCCAGAGATTTCCTT
TACTTTAGTTAATGAGGGTAAAGAATTTTTGAAAACGGCTGGAAATGGTGATTTACGTCAGGTTATTGCTGCAATTTATG
GCATAGGGACAGCGAAAAAAATGCGTCAAATCAAGGGCTCAGACTTAGATTTTGAACTAACAGGTTATGTCAGCATACCA
GAGCTGACAAGGGCTAATCGTAATTATATTACGATTTTAATAAATGGTCGATTTATCAAAAACTTTTTATTGAATCGGGC
AATTTTAGAAGGATATGGCAATCGATTGATGGTGGGACGGTTCCCTTTTGCTATTTTATCGATTAAAATTGACCCAACAC
TTGCTGATGTTAATGTTCATCCGACAAAACAAGAGGTGCGTTTGTCTAAAGAGCGTGAATTGATGGCTTTAATTTCTAAA
GCAATTGATGAGGCTTTATCAGAAGGTGTTTTGATTCCAGAAGCTTTGGAAAATTTGCAAGGAAGAGCTAAAGAAAAGGA
AACTCTTTCTGTTCAAACGGAACTTCCTTTGCAAAATAATCCTTTATATTATGATAATGTTCGCCAAGATTTTTATGTCA
GAGAAGAGGCAACTTTTAAAATCAATAAAAATCAGCCTTCAAATGATTCGTCTGAACAAACTTTTGATAATTTTACAGAA
AATCAACTTAATACAGATGCTGTCAATGAAAAAATTACTGACAGAACTGTTGAAAGTACAACTGAAATTACTGACAACAG
TCTAGAAAATACTGTCAGCAACTTTGAAATTGATTTTGATAATGAAGCAAAGATAAGTCAGTCATCAACTTTTCCGCAGC
TTGAATACTTGGCACAATTGCATGCGACTTATTTACTTTGTCAGTCCAAAGAAGGACTTTATTTGGTTGACCAACATGCG
GCTCAAGAGCGAATAAAATATGAGTATTGGAAAGATAAAATTGGTGAGGTCAGTATGGAGCAACAAATTTTACTTGCACC
ATATTTGTTCACTTTAGCCAAAAATGATTTTATTGTTTTAGCCGAGAAGAAAGATTTGTTGCATGAAGCCGGTGTTTTCT
TAGAAGAATACGGAGAAAATCAATTCATTTTAAGAGAACATCCAATCTGGTTAAAAGAAACCGAGATAGAGAAATCAATT
AATGAAATGATTGATATTATTCTCTCATCAAAAGAATTTTCACTCAAAAAATATCGTCATGATTTAGCTGCAATGGTTGC
TTGCAAAAGTTCAATTAAAGCTAATCATCCCCTTGATGCCGAATCAGCTAGAGCATTGCTTGCAGAATTAGCAACTTGTA
AAAATCCTTATAGTTGTGCGCATGGACGGCCAACGATTGTTCATTTTTCAGGGGATGACATTCAAAAAATGTTCCGGAGA
ATCCAAGAAACGCATCGTTCAAAAGCAGCTTCGTGGAAAGATTTTGAGTAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(455-598)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

56.836

99.238

0.564