Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   EKM74_RS11525 Genome accession   NZ_AP019306
Coordinates   2166803..2167372 (+) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain TUM9463     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2161803..2172372
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM74_RS11500 cysE 2163016..2163663 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  EKM74_RS11505 cysS 2163647..2165047 (+) 1401 WP_000631969.1 cysteine--tRNA ligase -
  EKM74_RS11510 - 2165040..2165444 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  EKM74_RS11515 rlmB 2165452..2166198 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  EKM74_RS11520 - 2166198..2166722 (+) 525 WP_000664737.1 NYN domain-containing protein -
  EKM74_RS11525 sigH 2166803..2167372 (+) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  EKM74_RS11530 rpmG 2167487..2167630 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  EKM74_RS11535 secE 2167686..2167868 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  EKM74_RS11540 nusG 2167881..2168429 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  EKM74_RS11545 rplK 2168610..2169032 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  EKM74_RS11550 rplA 2169240..2169932 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  EKM74_RS11560 rplJ 2170204..2170704 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  EKM74_RS11565 rplL 2170747..2171115 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  EKM74_RS11570 - 2171290..2171898 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=72316 EKM74_RS11525 WP_000872882.1 2166803..2167372(+) (sigH) [Staphylococcus aureus strain TUM9463]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=72316 EKM74_RS11525 WP_000872882.1 2166803..2167372(+) (sigH) [Staphylococcus aureus strain TUM9463]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment