Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NX050_RS15705 Genome accession   NZ_CP103456
Coordinates   2900864..2901520 (-) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis strain PN176 (HK176)     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2895864..2906520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX050_RS15680 (NX050_15680) spxH 2896074..2896973 (+) 900 WP_003245184.1 protease adaptor protein SpxH -
  NX050_RS15685 (NX050_15685) - 2897288..2897455 (+) 168 WP_003244944.1 hypothetical protein -
  NX050_RS15690 (NX050_15690) pepF 2897493..2899322 (-) 1830 WP_173401378.1 oligoendopeptidase F -
  NX050_RS15695 (NX050_15695) coiA 2899552..2900673 (-) 1122 WP_235091746.1 competence protein CoiA Machinery gene
  NX050_RS15700 (NX050_15700) - 2900747..2900869 (+) 123 WP_003245684.1 hypothetical protein -
  NX050_RS15705 (NX050_15705) mecA 2900864..2901520 (-) 657 WP_014479448.1 adaptor protein MecA Regulator
  NX050_RS15710 (NX050_15710) - 2901487..2901627 (-) 141 WP_119122854.1 hypothetical protein -
  NX050_RS15715 (NX050_15715) yjbE 2901797..2902453 (+) 657 WP_014479447.1 TerC family protein -
  NX050_RS15720 (NX050_15720) spx 2902496..2902891 (-) 396 WP_014476435.1 transcriptional regulator Spx -
  NX050_RS15725 (NX050_15725) yjbC 2903072..2903650 (-) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  NX050_RS15730 (NX050_15730) yjbB 2903814..2905031 (-) 1218 WP_072592593.1 MFS transporter -
  NX050_RS15735 (NX050_15735) oppF 2905139..2906056 (-) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=722898 NX050_RS15705 WP_014479448.1 2900864..2901520(-) (mecA) [Bacillus subtilis strain PN176 (HK176)]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=722898 NX050_RS15705 WP_014479448.1 2900864..2901520(-) (mecA) [Bacillus subtilis strain PN176 (HK176)]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995