Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   EKM72_RS10960 Genome accession   NZ_AP019305
Coordinates   2054443..2055012 (+) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain TUM9458     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2049443..2060012
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EKM72_RS10935 cysE 2050656..2051303 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  EKM72_RS10940 cysS 2051287..2052687 (+) 1401 WP_000631969.1 cysteine--tRNA ligase -
  EKM72_RS10945 - 2052680..2053084 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  EKM72_RS10950 rlmB 2053092..2053838 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  EKM72_RS10955 - 2053838..2054362 (+) 525 WP_000664737.1 NYN domain-containing protein -
  EKM72_RS10960 sigH 2054443..2055012 (+) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  EKM72_RS10965 rpmG 2055127..2055270 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  EKM72_RS10970 secE 2055326..2055508 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  EKM72_RS10975 nusG 2055521..2056069 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  EKM72_RS10980 rplK 2056250..2056672 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  EKM72_RS10985 rplA 2056880..2057572 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  EKM72_RS10995 rplJ 2057844..2058344 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  EKM72_RS11000 rplL 2058387..2058755 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  EKM72_RS11005 - 2058930..2059538 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=72273 EKM72_RS10960 WP_000872882.1 2054443..2055012(+) (sigH) [Staphylococcus aureus strain TUM9458]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=72273 EKM72_RS10960 WP_000872882.1 2054443..2055012(+) (sigH) [Staphylococcus aureus strain TUM9458]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment