Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PVF01_RS14610 Genome accession   NZ_CP118407
Coordinates   2942812..2943468 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain GABEEC10     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2937812..2948468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PVF01_RS14580 (PVF01_14520) yecA 2939064..2939729 (-) 666 WP_000847886.1 UPF0149 family protein YecA -
  PVF01_RS14600 (PVF01_14540) pgsA 2940378..2940926 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PVF01_RS14605 (PVF01_14545) uvrC 2940983..2942815 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PVF01_RS14610 (PVF01_14550) letA 2942812..2943468 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PVF01_RS14615 (PVF01_14555) yecU 2943764..2943940 (+) 177 WP_001307856.1 protein YecU -
  PVF01_RS14620 (PVF01_14560) yecF 2943927..2944151 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PVF01_RS14625 (PVF01_14565) sdiA 2944219..2944941 (-) 723 WP_021552828.1 transcriptional regulator SdiA -
  PVF01_RS14630 (PVF01_14570) tcyN 2945171..2945923 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PVF01_RS14635 (PVF01_14575) tcyL 2945920..2946588 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PVF01_RS14640 (PVF01_14580) dcyD 2946603..2947589 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=722309 PVF01_RS14610 WP_000611328.1 2942812..2943468(-) (letA) [Escherichia coli strain GABEEC10]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=722309 PVF01_RS14610 WP_000611328.1 2942812..2943468(-) (letA) [Escherichia coli strain GABEEC10]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482