Detailed information NTG0722307

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: NX823_RS13175
• Genome accession: NZ_CP103352
• Coordinates: 2470802..2473132 (-)
• Length: 776 a.a.
• NCBI ID: WP_069837640.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain SRCM117508
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2465802..2478132

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NX823_RS13140 (NX823_13140)	yqxA	2466141..2466479 (-)	339	WP_014477382.1	YqxA family protein	-
NX823_RS13145 (NX823_13145)	spoIIP	2466496..2467701 (-)	1206	WP_014477383.1	spore autolysin SpoIIP	-
NX823_RS13150 (NX823_13150)	gpr	2467764..2468870 (-)	1107	WP_014480309.1	GPR endopeptidase	-
NX823_RS13155 (NX823_13155)	rpsT	2469074..2469340 (+)	267	WP_003229989.1	30S ribosomal protein S20	-
NX823_RS13160 (NX823_13160)	holA	2469355..2470398 (-)	1044	WP_014480310.1	DNA polymerase III subunit delta	-
NX823_RS13165 (NX823_13165)	-	2470438..2470587 (-)	150	WP_003229985.1	hypothetical protein	-
NX823_RS13170 (NX823_13170)	yqzM	2470628..2470762 (+)	135	WP_003229983.1	YqzM family protein	-
NX823_RS13175 (NX823_13175)	comEC	2470802..2473132 (-)	2331	WP_069837640.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NX823_RS13180 (NX823_13180)	comEB	2473136..2473705 (-)	570	WP_003229978.1	ComE operon protein 2	-
NX823_RS13185 (NX823_13185)	comEA	2473772..2474389 (-)	618	WP_046160608.1	competence protein ComEA	Machinery gene
NX823_RS13190 (NX823_13190)	comER	2474473..2475294 (+)	822	WP_032726195.1	late competence protein ComER	-
NX823_RS13195 (NX823_13195)	yqeM	2475360..2476103 (-)	744	WP_069837641.1	class I SAM-dependent methyltransferase	-
NX823_RS13200 (NX823_13200)	rsfS	2476100..2476456 (-)	357	WP_014480315.1	ribosome silencing factor	-
NX823_RS13205 (NX823_13205)	yqeK	2476474..2477034 (-)	561	WP_014480316.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
NX823_RS13210 (NX823_13210)	nadD	2477024..2477593 (-)	570	WP_004398676.1	nicotinate-nucleotide adenylyltransferase	-
NX823_RS13215 (NX823_13215)	yhbY	2477605..2477895 (-)	291	WP_003226133.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 86668.24 Da
• Isoelectric Point: 7.2641

>NTDB_id=722307 NX823_RS13175 WP_069837640.1 2470802..2473132(-) (comEC) [Bacillus subtilis strain SRCM117508]
MRNSRLLLPMAAASATAGITAAAYFPAIFLFILFLLIILIKTRHAFLIIVCFFSFILFFVLYAVTDSQNVSSYRQGTYQF
KAVIDTIPKIDGDRMSMMVKTPDKEKWAAAYRIQSAGEKEQLLYIEPGMSCELTGTLEEPNHATVPGAFDYNEYLYRQHI
HWNYSVTSIQNCSEPENFKYKVLSLRKHIISFTNSLLPPDSAGIVQALTVGDRFYVEDEVLTAYQKLGVVHLLAISGLHV
GILTAGLFYIMIRLGITREKASILLLLFLPLYVMLTGAAPSVLRAALMSGVYLAGSLVKWRVHSATAICLSYIVLLLFNP
YHLFEAGFQLSFAVSFSLILSSSIFHQVKTSLGQLTIVSLIAQLGSLPILLYHFHQFSIISVPMNMLMVPFYTFCILPGA
VAGVLLLSLSVSFGRLFFSWFDLLISWTNRLITNIADVEVFTIMIAHPAPVLLFLFTVTIILLLMAIEKRSLSQLMVTGG
ICCTVMFLLFIYPCLSSEGEVDMIDIGQGDSMFVGAPHQRGRVLIDTGGTLSYSSEPWREKQHPFSLGEKVLIPFLTAKG
IKQLDALILTHADQDHIGEAETLLKHHKVKRLVIPKGFVSEPKDEKVLQTAREEGVTIEEVKRGDVLQIKDLQFHVLSPG
APDPASKNNSSLVLWMETGGMSWILTGDLEKEGEQEVMDVFPNIKADVLKVGHHGSKGSTGEEFIQQLQPKTAIISAGKN
NRYHHPHQEVLQLLQRHSIRVLRTDQNGTIQYRYKNRVGTFSVYPPYDTSDITETN

Nucleotide

• Length: 2331 bp

>NTDB_id=722307 NX823_RS13175 WP_069837640.1 2470802..2473132(-) (comEC) [Bacillus subtilis strain SRCM117508]
ATGCGTAATTCGCGTTTGTTATTGCCTATGGCGGCAGCTTCGGCAACGGCTGGAATTACTGCCGCCGCTTATTTCCCCGC
TATTTTTCTTTTCATCCTCTTTCTCCTCATCATTTTAATCAAAACGAGGCACGCTTTTCTTATTATTGTTTGTTTCTTCT
CTTTTATATTGTTTTTTGTACTGTATGCAGTCACAGATTCTCAGAATGTCTCTTCCTATCGGCAGGGAACCTATCAATTC
AAGGCAGTGATTGACACTATTCCCAAAATTGACGGCGACCGTATGTCTATGATGGTTAAGACACCTGATAAGGAAAAATG
GGCTGCTGCGTATCGCATTCAGTCTGCTGGTGAAAAAGAACAGCTGTTATACATAGAACCAGGAATGTCATGTGAGTTGA
CTGGTACATTGGAAGAACCGAATCACGCAACTGTGCCGGGTGCATTTGATTATAACGAGTATCTTTATCGGCAGCATATT
CATTGGAACTACTCTGTCACGTCTATTCAAAACTGCAGCGAACCTGAAAATTTTAAGTACAAGGTGCTCAGCTTGAGAAA
ACATATCATATCATTCACAAACAGCCTTTTGCCTCCTGATTCGGCAGGGATTGTACAGGCACTTACAGTTGGTGACAGAT
TTTATGTGGAGGATGAAGTGCTTACCGCGTATCAAAAGCTTGGTGTTGTCCATCTCTTGGCAATATCAGGACTCCACGTG
GGGATTTTGACAGCAGGTTTGTTTTATATCATGATTCGCCTTGGTATAACTAGAGAAAAGGCGTCAATTCTGTTGCTGTT
ATTTCTGCCGCTCTATGTGATGTTGACCGGCGCTGCTCCTTCAGTGCTACGCGCCGCTCTCATGTCGGGTGTTTACTTAG
CTGGAAGCCTTGTCAAATGGCGTGTCCACTCTGCAACTGCAATTTGTCTTTCATACATCGTCCTTCTGCTCTTCAATCCT
TATCATCTCTTTGAAGCCGGTTTTCAGCTATCGTTCGCCGTCAGTTTTTCTTTAATTCTATCCTCTTCTATTTTTCATCA
GGTTAAAACCTCCTTGGGGCAGCTGACAATTGTATCACTCATCGCTCAGCTGGGCTCGCTTCCGATTCTCCTATATCATT
TTCATCAGTTTTCTATCATCAGCGTACCGATGAATATGTTGATGGTACCATTTTATACCTTCTGTATTTTGCCGGGAGCT
GTAGCAGGTGTTCTTCTATTAAGTCTTTCCGTTTCGTTTGGGAGATTGTTTTTCAGCTGGTTTGATTTATTGATAAGCTG
GACCAATAGGCTAATCACAAACATTGCAGATGTTGAAGTGTTCACGATTATGATCGCACATCCTGCACCTGTTTTGCTTT
TTTTATTCACGGTCACGATCATCCTATTGCTTATGGCGATTGAAAAACGCTCCTTGTCGCAGTTGATGGTAACCGGAGGC
ATTTGCTGCACGGTGATGTTTCTGCTCTTTATATATCCGTGTCTTAGTTCCGAAGGAGAAGTGGATATGATAGATATTGG
ACAGGGTGACAGCATGTTTGTAGGTGCTCCGCATCAGCGGGGGCGTGTCTTAATTGATACCGGCGGCACTTTGTCTTACT
CGTCAGAGCCTTGGCGCGAAAAACAGCATCCGTTTTCACTGGGGGAAAAGGTGCTGATTCCGTTTTTAACTGCTAAGGGA
ATCAAACAGCTTGACGCTTTAATTCTGACGCACGCTGACCAAGATCATATCGGAGAGGCGGAGACTCTGCTGAAGCATCA
TAAAGTAAAGCGCCTCGTGATTCCGAAAGGGTTCGTTTCTGAACCTAAAGATGAGAAAGTGCTGCAGACAGCCAGAGAAG
AGGGAGTGACAATTGAAGAGGTGAAGCGAGGCGATGTATTGCAAATAAAGGATTTGCAGTTCCATGTACTGTCACCTGGA
GCACCTGATCCGGCAAGCAAAAATAATTCCTCTCTCGTTCTGTGGATGGAGACGGGCGGTATGAGCTGGATCTTGACGGG
TGACCTGGAGAAAGAAGGGGAACAGGAGGTGATGGACGTGTTTCCAAATATTAAAGCAGATGTCTTAAAGGTGGGGCACC
ATGGGAGCAAAGGCTCTACCGGTGAAGAATTCATCCAACAGCTTCAGCCGAAAACGGCCATTATCTCAGCCGGGAAAAAC
AATCGGTACCATCATCCTCATCAAGAAGTTCTGCAACTATTACAGAGACATTCTATCCGCGTGCTGCGAACAGATCAAAA
CGGAACGATCCAATATAGATACAAAAACAGAGTTGGAACCTTTTCTGTCTATCCTCCATATGATACATCAGATATAACAG
AGACGAACTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (208-469)

• Metallo-beta-lactamase superfamily (Lactamase_B) (507-718)

• Domain of unknown function (DUF4131) (DUF4131) (20-170)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	98.325	100	0.983