Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NX819_RS06570 Genome accession   NZ_CP103351
Coordinates   1253715..1254371 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis strain SRCM115947     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1248715..1259371
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX819_RS06540 (NX819_06540) oppF 1249178..1250095 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  NX819_RS06545 (NX819_06545) yjbB 1250203..1251420 (+) 1218 WP_080478438.1 MFS transporter -
  NX819_RS06550 (NX819_06550) yjbC 1251585..1252163 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  NX819_RS06555 (NX819_06555) spx 1252344..1252739 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  NX819_RS06560 (NX819_06560) yjbE 1252782..1253438 (-) 657 WP_003232944.1 TerC family protein -
  NX819_RS06565 (NX819_06565) - 1253608..1253748 (+) 141 WP_119122854.1 hypothetical protein -
  NX819_RS06570 (NX819_06570) mecA 1253715..1254371 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  NX819_RS06575 (NX819_06575) - 1254366..1254488 (-) 123 WP_003245684.1 hypothetical protein -
  NX819_RS06580 (NX819_06580) coiA 1254562..1255683 (+) 1122 WP_003232938.1 competence protein CoiA Machinery gene
  NX819_RS06585 (NX819_06585) pepF 1255913..1257742 (+) 1830 WP_173401378.1 oligoendopeptidase F -
  NX819_RS06590 (NX819_06590) - 1257780..1257947 (-) 168 WP_003244944.1 hypothetical protein -
  NX819_RS06595 (NX819_06595) spxH 1258261..1259160 (-) 900 WP_024573348.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=722203 NX819_RS06570 WP_003245194.1 1253715..1254371(+) (mecA) [Bacillus subtilis strain SRCM115947]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=722203 NX819_RS06570 WP_003245194.1 1253715..1254371(+) (mecA) [Bacillus subtilis strain SRCM115947]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1