Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   PVK49_RS08650 Genome accession   NZ_CP118306
Coordinates   1750295..1751062 (-) Length   255 a.a.
NCBI ID   WP_003058809.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain 20154608     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1745295..1756062
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PVK49_RS08635 (PVK49_08620) - 1747225..1748370 (-) 1146 WP_047236049.1 site-specific integrase -
  PVK49_RS08640 (PVK49_08625) dinD 1748628..1749482 (-) 855 WP_047236050.1 DNA damage-inducible protein D -
  PVK49_RS08645 (PVK49_08630) - 1749743..1749904 (-) 162 WP_168681587.1 hypothetical protein -
  PVK49_RS08650 (PVK49_08635) irvR 1750295..1751062 (-) 768 WP_003058809.1 helix-turn-helix transcriptional regulator Regulator
  PVK49_RS08655 (PVK49_08640) - 1751216..1751422 (+) 207 WP_002992503.1 helix-turn-helix transcriptional regulator -
  PVK49_RS08660 (PVK49_08645) - 1751456..1752223 (+) 768 WP_080343567.1 Bro-N domain-containing protein -
  PVK49_RS08665 (PVK49_08650) - 1752233..1752850 (+) 618 WP_047236051.1 Bro-N domain-containing protein -
  PVK49_RS08670 (PVK49_08655) - 1752877..1753119 (+) 243 WP_000648623.1 hypothetical protein -
  PVK49_RS08675 (PVK49_08660) - 1753376..1753708 (+) 333 WP_002992497.1 hypothetical protein -
  PVK49_RS08680 (PVK49_08665) - 1753708..1753899 (+) 192 WP_080032246.1 hypothetical protein -
  PVK49_RS08685 (PVK49_08670) - 1753911..1754273 (+) 363 WP_047236052.1 hypothetical protein -
  PVK49_RS08690 (PVK49_08675) - 1754270..1754578 (+) 309 WP_047236053.1 hypothetical protein -
  PVK49_RS08695 (PVK49_08680) - 1754581..1754853 (+) 273 WP_047236054.1 hypothetical protein -
  PVK49_RS08700 (PVK49_08685) - 1754854..1755720 (+) 867 WP_047236055.1 primase alpha helix C-terminal domain-containing protein -

Sequence

Protein


Download         Length: 255 a.a.        Molecular weight: 28725.00 Da        Isoelectric Point: 4.3544

>NTDB_id=721682 PVK49_RS08650 WP_003058809.1 1750295..1751062(-) (irvR) [Streptococcus pyogenes strain 20154608]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide


Download         Length: 768 bp        

>NTDB_id=721682 PVK49_RS08650 WP_003058809.1 1750295..1751062(-) (irvR) [Streptococcus pyogenes strain 20154608]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(23-68)

Peptidase S24-like (Peptidase_S24)

(141-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

34

100

0.4