Detailed information NTG0721556

Bioinformatically predicted

Overview

• Name: uvrC
• Type: Machinery gene
• Locus tag: PUW21_RS15565
• Genome accession: NZ_CP118167
• Coordinates: 2943562..2945334 (-)
• Length: 590 a.a.
• NCBI ID: WP_044052482.1
• Uniprot ID: -
• Organism: Bacillus subtilis strain 21855
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 2938562..2950334

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PUW21_RS15545 (PUW21_15545)	sdhA	2938781..2940541 (-)	1761	WP_003229567.1	succinate dehydrogenase flavoprotein subunit	-
PUW21_RS15550 (PUW21_15550)	sdhC	2940575..2941183 (-)	609	WP_003222512.1	succinate dehydrogenase cytochrome B558	-
PUW21_RS15555 (PUW21_15555)	yslB	2941476..2941922 (+)	447	WP_003222508.1	YslB family protein	-
PUW21_RS15560 (PUW21_15560)	lysCA	2941966..2943192 (-)	1227	WP_003229564.1	aspartate kinase	-
PUW21_RS15565 (PUW21_15565)	uvrC	2943562..2945334 (-)	1773	WP_044052482.1	excinuclease ABC subunit UvrC	Machinery gene
PUW21_RS15570 (PUW21_15570)	trxA	2945470..2945784 (-)	315	WP_003222500.1	thioredoxin	-
PUW21_RS15575 (PUW21_15575)	abfB	2946107..2947594 (-)	1488	WP_026009861.1	alpha-L-arabinofuranosidase AbfB	-
PUW21_RS15580 (PUW21_15580)	etfA	2947809..2948786 (-)	978	WP_003229553.1	electron transfer flavoprotein subunit alpha	-
PUW21_RS15585 (PUW21_15585)	etfB	2948822..2949595 (-)	774	WP_014480500.1	electron transfer flavoprotein subunit beta	-

Sequence

Protein

• Length: 590 a.a.
• Molecular weight: 68548.38 Da
• Isoelectric Point: 9.4732

>NTDB_id=721556 PUW21_RS15565 WP_044052482.1 2943562..2945334(-) (uvrC) [Bacillus subtilis strain 21855]
MNKQLKEKLALLPDQPGCYLMKDRQQTVIYVGKAKVLKNRVRSYFTGSHDAKTQRLVTEIEDFEYIVTSSNLEALILEMN
LIKKHDPKYNVMLKDDKTYPFIKLTHERHPRLIVTRNVKKDKGRYFGPYPNVQAARETKKLLDRLYPLRKCSKLPDRVCL
YYHLGQCLAPCVKDISEETNRELVESITRFLRGGYNEVKKELEEKMHEAAENLEFERAKELRDQMAHIESTMEKQKMTMN
DLVDRDVFAYAYDKGWMCVQVFFIRQGKLIERDVSMFPLYQEADEEFLTFIGQFYSKNNHFLPKEILVPDSVDQSMIEQL
LETNVHQPKKGPKKELLMLAHKNAKIALKEKFSLIERDEERSIGAVQKLGEALNIYTPHRIEAFDNSNIQGTNPVSAMIV
FIDGKPYKKEYRKYKIKTVTGPDDYGSMREVVRRRYTRVLRENLPLPDLIIIDGGKGQINAARDVIENELGLDIPIAGLA
KDEKHRTSNLLIGEPLEVVYLERNSQEFYLLQRIQDEVHRFAISFHRQIRGKSAFQSVLDDIPGIGEKRKKMLLKHFGSV
KKMKEASLEDIKKAGVPTAAAQLLYDKLQK

Nucleotide

• Length: 1773 bp

>NTDB_id=721556 PUW21_RS15565 WP_044052482.1 2943562..2945334(-) (uvrC) [Bacillus subtilis strain 21855]
ATGAACAAACAACTGAAAGAAAAACTCGCTCTCCTTCCTGATCAACCGGGTTGTTATCTCATGAAGGACCGGCAGCAGAC
TGTGATCTACGTAGGGAAAGCAAAAGTGCTGAAAAACAGAGTGCGCTCCTACTTCACCGGTTCTCACGACGCGAAAACCC
AAAGGCTTGTGACGGAAATCGAGGATTTTGAATATATCGTGACGTCCTCCAATCTTGAAGCGCTTATTTTAGAAATGAAT
CTGATCAAAAAGCATGATCCGAAATACAACGTCATGCTCAAAGACGACAAAACCTATCCTTTCATAAAACTCACCCATGA
ACGCCACCCAAGGCTGATTGTCACCCGCAATGTCAAAAAAGACAAAGGGCGCTATTTCGGGCCGTATCCGAATGTACAGG
CAGCAAGGGAAACAAAAAAACTGCTCGACCGTCTGTATCCTCTCAGAAAATGCTCCAAGCTCCCGGACAGAGTGTGCCTT
TACTATCATCTGGGCCAATGCCTCGCTCCGTGTGTAAAGGATATTTCCGAAGAGACGAACAGAGAGCTGGTTGAAAGCAT
TACACGTTTCTTAAGGGGCGGCTATAATGAGGTCAAAAAAGAGCTTGAAGAGAAAATGCATGAAGCTGCTGAGAATCTTG
AGTTTGAACGAGCAAAAGAGCTTCGTGACCAAATGGCCCATATTGAATCAACGATGGAAAAACAAAAAATGACGATGAAC
GATCTAGTCGACCGTGATGTGTTCGCGTACGCGTACGATAAGGGCTGGATGTGCGTGCAGGTCTTTTTCATCCGCCAAGG
AAAGCTCATTGAACGCGATGTCAGCATGTTCCCGCTTTATCAGGAAGCAGATGAAGAGTTCCTCACGTTCATCGGGCAGT
TCTATTCAAAAAACAACCACTTCCTTCCGAAGGAGATTTTAGTTCCGGACAGCGTAGATCAATCTATGATCGAGCAGCTG
CTGGAAACAAACGTTCACCAGCCGAAAAAAGGCCCGAAAAAAGAACTGCTCATGCTTGCCCATAAAAATGCGAAAATCGC
ATTGAAAGAAAAATTCTCTTTAATCGAACGGGACGAGGAGCGTTCAATCGGGGCAGTGCAGAAACTAGGTGAGGCATTAA
ATATTTATACGCCGCACAGAATTGAAGCGTTTGATAACTCAAATATACAGGGGACAAACCCGGTTTCCGCGATGATTGTG
TTTATCGATGGCAAACCATACAAAAAGGAATACCGCAAATATAAAATCAAAACTGTTACAGGGCCGGATGATTACGGTTC
TATGAGAGAGGTTGTCAGAAGACGCTATACGAGAGTGCTTCGTGAGAATCTGCCGCTGCCCGATCTGATTATCATTGACG
GAGGAAAAGGGCAGATCAACGCAGCAAGGGATGTCATTGAAAATGAACTCGGCTTGGATATCCCGATCGCCGGTCTAGCG
AAAGATGAAAAACACAGAACCTCAAATTTACTGATCGGTGAGCCGCTGGAGGTAGTGTATCTGGAACGAAACAGCCAGGA
ATTTTACCTCCTGCAGCGCATTCAAGACGAGGTGCACCGTTTTGCAATCAGTTTTCACAGGCAAATCCGCGGAAAAAGCG
CGTTTCAATCCGTTTTGGACGACATCCCGGGTATCGGAGAGAAAAGAAAGAAAATGCTGTTAAAGCATTTCGGTTCCGTT
AAAAAAATGAAGGAAGCAAGCCTTGAGGACATCAAAAAAGCCGGTGTTCCCACAGCGGCGGCTCAGCTCCTTTACGACAA
ATTGCAAAAATAA

Domains

Predicted by InterProScan.

• UvrB/uvrC motif (UVR) (197-229)

• UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom) (373-523)

• GIY-YIG catalytic domain (GIY-YIG) (16-90)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
uvrC	Streptococcus pneumoniae TIGR4	59.014	99.661	0.588
uvrC	Streptococcus pneumoniae R6	58.673	99.661	0.585
uvrC	Streptococcus pneumoniae D39	58.673	99.661	0.585