Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL334_RS02045 Genome accession   NZ_AP019192
Coordinates   368949..369638 (+) Length   229 a.a.
NCBI ID   WP_033705362.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ASP0581     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 363949..374638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL334_RS02020 (ASP0581_03750) gpsB 364059..364388 (+) 330 WP_000146522.1 cell division regulator GpsB -
  EL334_RS02030 (ASP0581_03760) - 364874..366031 (+) 1158 WP_033705364.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  EL334_RS02035 (ASP0581_03770) mapZ 366043..367437 (+) 1395 WP_000039303.1 cell division site-positioning protein MapZ -
  EL334_RS02040 (ASP0581_03780) gndA 367513..368937 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  EL334_RS02045 (ASP0581_03790) covR 368949..369638 (+) 690 WP_033705362.1 response regulator transcription factor Regulator
  EL334_RS02050 (ASP0581_03800) cbpC 369736..370752 (+) 1017 WP_033705361.1 choline-binding protein CbpC -
  EL334_RS02055 (ASP0581_03810) mvk 370874..371752 (+) 879 WP_000163323.1 mevalonate kinase -
  EL334_RS02060 (ASP0581_03820) mvaD 371734..372687 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  EL334_RS02065 (ASP0581_03830) - 372674..373681 (+) 1008 WP_033705360.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26958.32 Da        Isoelectric Point: 6.9836

>NTDB_id=72119 EL334_RS02045 WP_033705362.1 368949..369638(+) (covR) [Streptococcus pneumoniae strain ASP0581]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALFMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=72119 EL334_RS02045 WP_033705362.1 368949..369638(+) (covR) [Streptococcus pneumoniae strain ASP0581]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTTCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment